The Immunoregulatory Mechanisms of Human Cytomegalovirus from Primary Infection to Reactivation. [PDF]
Liu X, Liu C, Zhang T.
europepmc +1 more source
Status and future of recombinant adeno‐associated virus vector manufacturing
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley +1 more source
Interstrain recombinants of human cytomegalovirus uncouple glycoprotein display, virion infectivity, and spread characteristics. [PDF]
Peterson CS +4 more
europepmc +1 more source
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson +7 more
wiley +1 more source
Human cytomegalovirus-triggered necroptosis is suppressed by sequestration of MLKL in the nucleus of infected monocytes. [PDF]
Geiler BW +4 more
europepmc +1 more source
Measuring the Burden of Choice: Development and Validation of a Choice Overload Scale
ABSTRACT Excessive choice imposes substantial cognitive demands on consumers, impair decision‐making, and generate negative consumer responses—a phenomenon widely known as the choice overload effect. Despite its conceptual prominence in consumer research and its enduring relevance in today's consumer markets, existing approaches to measuring choice ...
Jennifer Musial
wiley +1 more source
Human cytomegalovirus control in allogeneic stem cell transplant recipients in the letermovir era - emerging humoral and cellular players. [PDF]
Lauruschkat CD +11 more
europepmc +1 more source
ABSTRACT Cosmetics production and consumption, which have been growing steadily in recent years, are associated with a number of negative environmental, moral, and health impacts. This study examines the influence of cosmetics producers' corporate social responsibility (CSR) communication on the formation of purchase intention among Czech consumers ...
Libena Tetrevova +4 more
wiley +1 more source
Human Cytomegalovirus Associated Neuropathies: A Comprehensive Review From Pathophysiology to Clinical and Therapeutic Considerations. [PDF]
Behanan N +4 more
europepmc +1 more source

