Results 191 to 200 of about 138,822 (261)

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Coding-complete genome of human cytomegalovirus extracted from a nasopharyngeal swab in Brazil. [PDF]

Microbiol Resour Announc
Cruz AMS, Sousa EC, Barbagelata LS, das Chagas WD, Nunes AMS, Livorati MTFP, de Almeida WAF, da Trindade JF, Costa AS, Tavares FN, de Sousa MS, Dos Santos MC.   +11 more
europepmc   +1 more source

Screening of bispecific antibodies during single cell cloning of recombinant Chinese hamster ovary cell lines to improve titer and product quality

Biotechnology Progress, EarlyView.
Abstract Development of therapeutic bispecific antibodies (BsAbs) poses significant manufacturability challenges associated with correct chain pairing and an increased diversity of impurities. Here we address this with a product quality assessment during cell line development (CLD), forgoing the need for genetic characterization during cell line ...
Molly Robinson, Jessica Willmott, Holly Corrigall, Daniela Lega, Joseph Stirling, Vithiya Vimalraj, Mitul Patel, Robyn Emmins   +7 more
wiley   +1 more source

Human cytomegalovirus infection and cognitive decline: insights from population and experimental studies. [PDF]

Front Aging Neurosci
Yaiw KC, Ferrer IA, Söderberg-Nauclér C, Religa D.   +3 more
europepmc   +1 more source

Beauty With a Conscience: The Power of CSR Communication Dimensions in the Formation of Purchase Intention Among Cosmetics Consumers

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Cosmetics production and consumption, which have been growing steadily in recent years, are associated with a number of negative environmental, moral, and health impacts. This study examines the influence of cosmetics producers' corporate social responsibility (CSR) communication on the formation of purchase intention among Czech consumers ...
Libena Tetrevova, Martina Jelinkova, Simona Munzarova, Alexandra Kocurikova, Michal Patak   +4 more
wiley   +1 more source

Practice adoption in MNCS: A multi‐level interactionist model of trait activation

Global Strategy Journal, EarlyView.
Abstract Research Summary Sharing knowledge through organizational practices is an important source of advantage for multinational corporations (MNCs). While prior research on practice adoption by subsidiaries of MNCs has identified several individual and organizational factors, this study examines their interplay in the context of HQ‐mandated ...
Sven Kunisch, Ulrich Leicht‐Deobald, Tomi Laamanen, Adrian Schulte Steinberg, Björn Ambos   +4 more
wiley   +1 more source

The immunomodulatory role of human cytomegalovirus in cancer in the era of checkpoint immunotherapy. [PDF]

Philos Trans R Soc Lond B Biol Sci
Bremke J, Jay C, Little M, Fairfax BP.
europepmc   +1 more source

Reframing Technology and Ethics in Corneal Xenotransplantation: A Scoping Review of Standards and Safety in Ophthalmology

Health Care Science, EarlyView.
Bringing attention to the moral dilemmas raised by xenotransplantation and the continuous creation of standardized frameworks for donor technology and biosafety risk management, with a focus on striking a balance between patient safety, medical innovation, and ethical obligation.
Sankhajyoti Saha, Moubani Dutta, Agnihiya Bosu   +2 more
wiley   +1 more source

The human cytomegalovirus chemokine binding protein UL22A is necessary for efficient reactivation from latency in CD34⁺ hematopoietic progenitor cells and humanized mice. [PDF]

J Virol
Turner RL, Diggins NL, Slind L, Mitchell J, Pham AH, Parkins CJ, Perez W, Medica S, Denton M, Andoh TF, Webb GM, Andrade-Vera D, Streblow DN, Caposio P, Hancock MH.   +14 more
europepmc   +1 more source

Lytic or Latent Phase in Human Cytomegalovirus Infection: An Epigenetic Trigger. [PDF]

Int J Mol Sci
Cevenini A, De Antonellis P, Mazzarelli LL, Sarno L, D'Alessandro P, Pellicano M, Salomè S, Raimondi F, Guida M, Maruotti GM, Miceli M.   +10 more
europepmc   +1 more source