Results 211 to 220 of about 134,051 (264)
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The pathogenesis of human cytomegalovirus
The Journal of Pathology, 2014AbstractHuman cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft recipient and AIDS patients. More recently, it has been recognized as a pathogen for those admitted to intensive care units, for the elderly and for the general population.
Paul, Griffiths +2 more
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British Journal of Midwifery, 1995
Human cytomegalovirus is one virus of which pregnant women are not generally made aware, although it causes disease and disability in up to 400 babies in Britain every year. This article focuses on the epidemiology of the virus, with particular reference to pregnancy, issues surrounding humoral immunity, diagnosis and prenatal screening.
K. Radsak +5 more
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Human cytomegalovirus is one virus of which pregnant women are not generally made aware, although it causes disease and disability in up to 400 babies in Britain every year. This article focuses on the epidemiology of the virus, with particular reference to pregnancy, issues surrounding humoral immunity, diagnosis and prenatal screening.
K. Radsak +5 more
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Cytomegalovirus and human immunosenescence
Reviews in Medical Virology, 2008Abstract‘Immunosenescence’ is an imprecise term used to describe deleterious age‐associated changes to immune parameters observed in all mammals studied so far. Primarily anecdotal evidence implies that failing immunity is responsible for the increased incidence and severity of infectious disease in old people.
Graham, Pawelec +4 more
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New England Journal of Medicine, 1972
KNOWLEDGE of the usual modes of transmission of cytomegalovirus (CMV) infection is incomplete.1 The possibility of viral transmission from infected cervical secretions to infants at the time of del...
K, Hayes, D M, Danks, H, Gibas, I, Jack
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KNOWLEDGE of the usual modes of transmission of cytomegalovirus (CMV) infection is incomplete.1 The possibility of viral transmission from infected cervical secretions to infants at the time of del...
K, Hayes, D M, Danks, H, Gibas, I, Jack
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2008
Human cytomegalovirus (HCMV) contains a large and complex E-type genome. There are both clinical isolates of the virus that have been passaged minimally in fibroblasts and so-called laboratory strains that have been extensively passaged and adapted to growth in fibroblasts. The genomes of laboratory strains have undergone rearrangements.
E, Murphy, T, Shenk
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Human cytomegalovirus (HCMV) contains a large and complex E-type genome. There are both clinical isolates of the virus that have been passaged minimally in fibroblasts and so-called laboratory strains that have been extensively passaged and adapted to growth in fibroblasts. The genomes of laboratory strains have undergone rearrangements.
E, Murphy, T, Shenk
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Human Cytomegalovirus microRNAs
2008MicroRNAs (miRNAs) are approximately 22 nucleotide RNAs that mediate the posttranscriptional regulation of gene expression. miRNAs regulate diverse cellular processes such as development, differentiation, cell cycling, apoptosis, and immune responses.
P J, Fannin Rider +3 more
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Human cytomegalovirus labyrinthitis
American Journal of Otolaryngology, 1990The purpose of this report is to present a review of the clinical and histopathologic findings in human cytomegalovirus (HCMV) labyrinthitis. Human cytomegalovirus infection was first recognized in its congenital disseminated form and, subsequently, in a subclinical form.
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Human Monoclonal Antibodies to Human Cytomegalovirus
The Journal of Infectious Diseases, 1989Human monoclonal antibodies (HMAbs) to human cytomegalovirus (HCMV) have been developed by using electric field-induced cell fusion of human B lymphocytes to the human-mouse cell line SBC-H20. By this procedure, multiple hybridomas have been produced that secrete IgG 1 HMAbs with distinct patterns of indirect immunofluorescence on HCMV-infected cells ...
S K, Foung +6 more
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Inactivation of human cytomegalovirus by phytohemagglutinin
Archives of Virology, 1978Human cytomegalovirus (CMV) was inactivated by treatment with phytohemagglutinin (PHA) in contrast to herpes simplex virus (HSV), which was not. Approximately 90% of infectivity was lost following exposure of CMV to PHA. Greater reduction of infectivity, more than 99%, was obtained following pretreatment of cells with PHA than by direct mixture of the ...
M, Ito, L, Girvin, A L, Barron
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Human cytomegalovirus infection and atherothrombosis
Journal of Thrombosis and Thrombolysis, 2011Vascular endothelium, as a key regulator of hemostasis, mediates vascular dilatation, prevents platelet adhesion, and inhibits thrombin generation. Endothelial dysfunction caused by acute or chronic inflammation, such as in atherosclerosis, creates a proinflammatory environment which supports leukocyte transmigration toward inflammatory sites, and at ...
Popović, Milan +5 more
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