Results 131 to 140 of about 138,822 (261)

Seroprevalence of human cytomegalovirus in blood donors. [PDF]

GMS Hyg Infect Control
Kanna ALK, Mathialagan AM, Paari S, Mardawada H.   +3 more
europepmc   +1 more source

Lactylation‐Driven PROS1‐TYRO3‐CARF Signaling Promotes Therapy‐Induced Senescence Escape and Radioresistance in Meningioma

Advanced Science, EarlyView.
A glycolysis‐driven epigenetic switch promotes therapy resistance in meningioma. Increased lactate production enhances histone H3K27 lactylation, which activates PROS1 secretion. Secreted PROS1 engages TYRO3 signaling to degrade the senescence regulator CARF, allowing cancer cells to escape growth arrest.
Zhuohang Wang, Qixiang Zhang, Keman Liao, Xiaoyu Liu, Hongchi Zhang, Yunsheng Chen, Yuxiao Ma, Yikui Liu, Aoqian Xu, Yuhao Sun, Jiayi Chen, Liuguan Bian, Baofeng Wang   +12 more
wiley   +1 more source

Human Cytomegalovirus as a Therapeutic Target in Glioma Stem Cells. [PDF]

Cells
Bou Dargham T, Vaios EJ, Lawler S, Batich K.   +3 more
europepmc   +1 more source

Phase II Study of Posttransplant Cyclophosphamide‐Based Graft‐Versus‐Host Disease Prophylaxis After HLA‐Mismatched Unrelated Donor Reduced Intensity Transplantation: Results From the ACCESS Trial Expansion Cohort

American Journal of Hematology, EarlyView.
ABSTRACT Posttransplant cyclophosphamide (PTCy) to prevent graft‐versus‐host disease (GVHD) improves outcomes in recipients of HLA mismatched unrelated donor (MMUD) allogeneic hematopoietic cell transplantation (allo HCT). Outcomes of MMUD HCT using PTCy in patients requiring reduced intensity or non‐myeloablative conditioning (RIC/NMA) are not well ...
Brian C. Shaffer, Monzr M. Al Malki, Antonio Martin Jimenez Jimenez, Joseph Stanek, Stephanie Bo‐Subait, Brent R. Logan, Jianqun Kou, Erin Leckrone, Heather E. Stefanski, Stephen R. Spellman, Craig Malmberg, Medhat Askar, Rachel Cusatis, Dipenkumar Modi, Farhad Khimani, Mehdi Hamadani, Martin Maiers, Rachel Cook, Karen Ballen, Javier Bolaños‐Meade, Uttam Rao, Jordan Milner, Ramzi Abboud, Katarzyna Jamieson, George Carrum, Bhagirathbhai Dholaria, William J. Hogan, Ran Reshef, Satyajit Kosuri, Alison Loren, Karilyn Larkin, Sally Arai, Muna Qayed, Sung Won Choi, Larisa Broglie, Jeffery J. Auletta, Bronwen E. Shaw, Steven M. Devine, Mahasweta Gooptu   +38 more
wiley   +1 more source

Nuclear transport of human cytomegalovirus tegument protein pp65 through nucleoplasmic reticulum. [PDF]

PLoS Pathog
Azzeh M, Santos MF, Yokomizo AMK, Cha V, Corbeil D, Lorico A.   +5 more
europepmc   +1 more source

PUS7 Deficiency: Phenotypical Expansion of PUS7‐Related Neurodevelopmental Disorders

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Pathogenic variants in PUS7, encoding pseudouridine synthase 7, cause a rare neurodevelopmental disorder marked by intellectual disability, microcephaly, short stature, and behavioral disturbances. Since the first report in 2018, only 16 patients have been described.
Alice Muda, Barbara Belmessieri, Patrizia Accorsi, Jessica Galli, Edoardo Errichiello, Lucio Giordano   +5 more
wiley   +1 more source

Validation of low-volume plasma dilution protocols for human cytomegalovirus DNA quantification using the cobas CMV assay. [PDF]

Microbiol Spectr
Lim G, Kim J-H, Joo H-J, Jeon H-K, Ryu MR, Yun SA, Shin A, Kim DR, Kim Y-J, Kim TY, Huh HJ.   +10 more
europepmc   +1 more source

Genotype–Phenotype Correlations of Monoallelic PFIC Variants in Pediatric Liver Disease: A Multicenter Retrospective Cohort Study

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is classically caused by biallelic pathogenic variants, yet monoallelic variants of uncertain significance (VUS) in PFIC‐associated genes are increasingly identified in children with cholestasis, creating diagnostic uncertainty.
Brett J. Hoskins, Tiziano Pramparo, Chaowapong Jarasvaraparn, Michael J. Wilsey, Voytek Slowik, Lakshmi Kunam, Janis M. Stoll, Ruben E. Quiros‐Tejeira, Simon Lam, Wikrom Karnsakul   +9 more
wiley   +1 more source

Toward point-of-care and amplification-free detection of human cytomegalovirus using CRISPR-Cas12a. [PDF]

iScience
Kohabir KAV, Rietveld AWJ, Nooi LO, Beijer RE, van Dongen JE, Linthorst J, Wolthuis RMF, Jonges M, Welkers MRA, Segerink LI, Sistermans EA.   +10 more
europepmc   +1 more source

Human Cytomegalovirus (HCMV) – Revised [PDF]

Transfusion Medicine and Hemotherapy, 2010
Schottstedt, Volkmar, Blümel, Johannes, Burger, Reinhard, Drosten, Christian, Gröner, Albrecht, Gürtler, Lutz G., Heiden, Margarethe, Hildebrandt, Martin, Jansen, Bernd, Montag-Lessing, Thomas, Offergeld, Ruth, Pauli, Georg, Seitz, Rainer, Schlenkrich, Uwe, Strobel, Johanna, Willkommen, Hannelore, Wirsing von König, Carl-Heinz   +16 more
openaire   +3 more sources