Results 221 to 230 of about 8,385,867 (288)

Population Pharmacokinetics and Exposure–Response Relationships of Maribavir in Transplant Recipients With First Episode or Refractory Cytomegalovirus

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Maribavir's anti‐cytomegalovirus (CMV) activity and favorable safety/tolerability profile is a welcomed addition to the CMV treatment armamentarium. To further characterize pharmacokinetic (PK) and exposure–response relationships of maribavir in transplant recipients with CMV, a population PK model was updated with data from the AURORA study ...
Kefeng Sun, Claudia Jomphe, Nathalie H. Gosselin, Leon Pheng, Chandrasekar Durairaj, Yaming Hang, Indranil Bhattacharya   +6 more
wiley   +1 more source

RAF1 promotes successful human cytomegalovirus replication and is regulated by AMPK-mediated phosphorylation during infection. [PDF]

J Virol
Dunn DM, Pack LJ, Munger JC.
europepmc   +1 more source

Modulation of Monocyte Effector Functions and Gene Expression by Human Cytomegalovirus Infection. [PDF]

Viruses
Planchon MS, Fishman JA, El Khoury J.
europepmc   +1 more source

Sustainability Leverage, Customer Orientation and Firm Performance—An Empirical Study of Small Medium Enterprises in Indonesia

Sustainable Development, EarlyView.
ABSTRACT This research explores how resource‐based views (RBV) and institutional pressures affect sustainability practices in SMEs and examines the impact of customer orientation on their performance. Evidence linking sustainable practices to enhanced SME performance is limited. A total of 305 SMEs participated in the survey, and the data were analyzed
Clare D'Souza, Marthin Nanere, Malliga Marimuthu, Mokhamad Arwani, Dung Nguyen, Ninh Nguyen   +5 more
wiley   +1 more source

¹H NMR Urinary Metabolomics Profiling of Newborns with Congenital Human Cytomegalovirus Infection: Insights into Metabolic Alterations. [PDF]

J Proteome Res
Spadavecchia A, Zoccarato M, Tedone G, Biolatti M, Dell'Oste V, Leone A, Cossard A, Sozzi M, Bresesti I, Bertino E, Gobetto R, Coscia A, Gallo A.   +12 more
europepmc   +1 more source

Human Cytomegalovirus-associated DNA Polymerase and Protein Kinase Activities

, 1981
Eng‐Chun Mar, Pravin Patel, Eng‐Shang Huang   +2 more
openalex   +1 more source

3D Quantification of Viral Transduction Efficiency in Living Human Retinal Organoids

Small Methods, EarlyView.
Optimization of viral vectors and their testing in human tissue is crucial to gene therapy development. Conventional technologies to assess virus transduction either lack spatial or temporal information. Here, spatiotemporal mapping of virus transduction in living retinal tissue is introduced, levering fluorescence imaging and machine learning‐based ...
Teresa S. Rogler, Katja A. Salbaum, Achim T. Brinkop, Selina M. Sonntag, Rebecca James, Elijah R. Shelton, Alina Thielen, Roland Rose, Sabrina Babutzka, Thomas Klopstock, Stylianos Michalakis, Friedhelm Serwane   +11 more
wiley   +1 more source

Rapid and Sensitive Detection of RNA Viruses through Imaging of Marker Molecules Derived from Designed Circular DNA Probes

Small Methods, EarlyView.
This study presents a rapid and sensitive virus detection method that employs imaging of virus‐specific DNA markers. Utilizing specially designed single‐stranded circular DNA probes, this method captures RNA fragments from RNase‐digested viral genomes during the reverse transcriptase‐based reaction, resulting in double‐stranded markers that are ...
Yoon‐ha Jang, Taesoo Kim, Su‐jin Hong, Se‐yeon Kim, Hyeseung Hwang, Siwon Kim, Su‐a Kang, Nabin Won, Dogeun Kim, Min Jae Kim, Yong Pil Chong, Seongsoo Jang, Kyubong Jo, Kwang‐il Lim   +13 more
wiley   +1 more source

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

Small Methods, EarlyView.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai, Jiawen Wang, Zihuan Lin, Danni Yu, Hui Yang, Jinsong Wei, Xiaoyu Li, Hao Hu, Chao Ni, Bing Zhao   +9 more
wiley   +1 more source

Erratum for Leber, "Maternal and congenital human cytomegalovirus infection: laboratory testing for detection and diagnosis". [PDF]

J Clin Microbiol
Leber AL.
europepmc   +1 more source