Results 241 to 250 of about 9,097,628 (294)
A Potent Inhibitor of Human Cytomegalovirus Infection Works Post-Entry Specifically in Differentiating Myelo-Monocytic Cells. [PDF]
PathogensMurray MJ +7 more
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New England Journal of Medicine, 1972
KNOWLEDGE of the usual modes of transmission of cytomegalovirus (CMV) infection is incomplete.1 The possibility of viral transmission from infected cervical secretions to infants at the time of del...
David M. Danks, Ian Jack, Kathleen Hayes
exaly +3 more sources
KNOWLEDGE of the usual modes of transmission of cytomegalovirus (CMV) infection is incomplete.1 The possibility of viral transmission from infected cervical secretions to infants at the time of del...
David M. Danks, Ian Jack, Kathleen Hayes
exaly +3 more sources
Pharmacology & Therapeutics, 2003
Human cytomegalovirus (HCMV), a betaherpesvirus, represents the major infectious cause of birth defects, as well as an important pathogen for immunocompromised individuals. The viral nucleocapsid containing a linear double-stranded DNA of 230 kb is surrounded by a proteinaceous tegument, which is itself enclosed by a loosely applied lipid bilayer ...
LANDOLFO, Santo Giuseppe +3 more
openaire +3 more sources
Human cytomegalovirus (HCMV), a betaherpesvirus, represents the major infectious cause of birth defects, as well as an important pathogen for immunocompromised individuals. The viral nucleocapsid containing a linear double-stranded DNA of 230 kb is surrounded by a proteinaceous tegument, which is itself enclosed by a loosely applied lipid bilayer ...
LANDOLFO, Santo Giuseppe +3 more
openaire +3 more sources
The pathogenesis of human cytomegalovirus
The Journal of Pathology, 2014AbstractHuman cytomegalovirus (HCMV) is a recognized cause of disease in the fetus, the allograft recipient and AIDS patients. More recently, it has been recognized as a pathogen for those admitted to intensive care units, for the elderly and for the general population.
Paul, Griffiths +2 more
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British Journal of Midwifery, 1995
Human cytomegalovirus is one virus of which pregnant women are not generally made aware, although it causes disease and disability in up to 400 babies in Britain every year. This article focuses on the epidemiology of the virus, with particular reference to pregnancy, issues surrounding humoral immunity, diagnosis and prenatal screening.
K. Radsak +5 more
openaire +2 more sources
Human cytomegalovirus is one virus of which pregnant women are not generally made aware, although it causes disease and disability in up to 400 babies in Britain every year. This article focuses on the epidemiology of the virus, with particular reference to pregnancy, issues surrounding humoral immunity, diagnosis and prenatal screening.
K. Radsak +5 more
openaire +2 more sources
Cytomegalovirus and human immunosenescence
Reviews in Medical Virology, 2008Abstract‘Immunosenescence’ is an imprecise term used to describe deleterious age‐associated changes to immune parameters observed in all mammals studied so far. Primarily anecdotal evidence implies that failing immunity is responsible for the increased incidence and severity of infectious disease in old people.
Graham, Pawelec +4 more
openaire +2 more sources
Preventing Infection by Human Cytomegalovirus. [PDF]
Journal of Infectious Diseases, 2020 Abstract The way to a successful vaccine against human cytomegalovirus is hampered by the peculiar biology of this infection. However, some candidate vaccines have been shown to protect seronegative women and transplant recipients, and we should know soon whether they can prevent congenital infection.
Stanley A Plotkin
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2008
Human cytomegalovirus (HCMV) contains a large and complex E-type genome. There are both clinical isolates of the virus that have been passaged minimally in fibroblasts and so-called laboratory strains that have been extensively passaged and adapted to growth in fibroblasts. The genomes of laboratory strains have undergone rearrangements.
E, Murphy, T, Shenk
openaire +2 more sources
Human cytomegalovirus (HCMV) contains a large and complex E-type genome. There are both clinical isolates of the virus that have been passaged minimally in fibroblasts and so-called laboratory strains that have been extensively passaged and adapted to growth in fibroblasts. The genomes of laboratory strains have undergone rearrangements.
E, Murphy, T, Shenk
openaire +2 more sources
Human Cytomegalovirus microRNAs
2008MicroRNAs (miRNAs) are approximately 22 nucleotide RNAs that mediate the posttranscriptional regulation of gene expression. miRNAs regulate diverse cellular processes such as development, differentiation, cell cycling, apoptosis, and immune responses.
P J, Fannin Rider +3 more
openaire +2 more sources