Results 261 to 270 of about 205,529 (308)
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Cytomegalovirus and human immunosenescence

Reviews in Medical Virology, 2008
Abstract‘Immunosenescence’ is an imprecise term used to describe deleterious age‐associated changes to immune parameters observed in all mammals studied so far. Primarily anecdotal evidence implies that failing immunity is responsible for the increased incidence and severity of infectious disease in old people.
Graham, Pawelec   +4 more
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Cytomegalovirus in Human Milk

New England Journal of Medicine, 1972
KNOWLEDGE of the usual modes of transmission of cytomegalovirus (CMV) infection is incomplete.1 The possibility of viral transmission from infected cervical secretions to infants at the time of del...
K, Hayes, D M, Danks, H, Gibas, I, Jack
openaire   +2 more sources

Human Cytomegalovirus Genome

2008
Human cytomegalovirus (HCMV) contains a large and complex E-type genome. There are both clinical isolates of the virus that have been passaged minimally in fibroblasts and so-called laboratory strains that have been extensively passaged and adapted to growth in fibroblasts. The genomes of laboratory strains have undergone rearrangements.
E, Murphy, T, Shenk
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Human Cytomegalovirus microRNAs

2008
MicroRNAs (miRNAs) are approximately 22 nucleotide RNAs that mediate the posttranscriptional regulation of gene expression. miRNAs regulate diverse cellular processes such as development, differentiation, cell cycling, apoptosis, and immune responses.
P J, Fannin Rider   +3 more
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Human cytomegalovirus labyrinthitis

American Journal of Otolaryngology, 1990
The purpose of this report is to present a review of the clinical and histopathologic findings in human cytomegalovirus (HCMV) labyrinthitis. Human cytomegalovirus infection was first recognized in its congenital disseminated form and, subsequently, in a subclinical form.
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Human Monoclonal Antibodies to Human Cytomegalovirus

The Journal of Infectious Diseases, 1989
Human monoclonal antibodies (HMAbs) to human cytomegalovirus (HCMV) have been developed by using electric field-induced cell fusion of human B lymphocytes to the human-mouse cell line SBC-H20. By this procedure, multiple hybridomas have been produced that secrete IgG 1 HMAbs with distinct patterns of indirect immunofluorescence on HCMV-infected cells ...
S K, Foung   +6 more
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Inactivation of human cytomegalovirus by phytohemagglutinin

Archives of Virology, 1978
Human cytomegalovirus (CMV) was inactivated by treatment with phytohemagglutinin (PHA) in contrast to herpes simplex virus (HSV), which was not. Approximately 90% of infectivity was lost following exposure of CMV to PHA. Greater reduction of infectivity, more than 99%, was obtained following pretreatment of cells with PHA than by direct mixture of the ...
M, Ito, L, Girvin, A L, Barron
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Pneumonitis in human cytomegalovirus infection

Current Infectious Disease Reports, 2006
Human cytomegalovirus (HCMV) is a beta herpes virus with a double stranded DNA genome of 240kbp. The virus is prevalent and establishes a latent infection in most adults. HCMV is an opportunistic pathogen for patients with impaired cellular immunity. HCMV pneumonia is a common presentation of HCMV disease in immunocompromised patients. The incidence of
Erik, Langhoff, Robert E, Siegel
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Overview of Human Cytomegalovirus Pathogenesis

2021
Human cytomegalovirus (HCMV) is a betaherpesvirus with a global seroprevalence of 60-90%. HCMV is the leading cause of congenital infections and poses a great health risk to immunocompromised individuals. Although HCMV infection is typically asymptomatic in the immunocompetent population, infection can result in mononucleosis and has also been ...
Heather L, Fulkerson   +3 more
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Human cytomegalovirus infection and atherothrombosis

Journal of Thrombosis and Thrombolysis, 2011
Vascular endothelium, as a key regulator of hemostasis, mediates vascular dilatation, prevents platelet adhesion, and inhibits thrombin generation. Endothelial dysfunction caused by acute or chronic inflammation, such as in atherosclerosis, creates a proinflammatory environment which supports leukocyte transmigration toward inflammatory sites, and at ...
Popović, Milan   +5 more
openaire   +4 more sources

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