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Defective virions of human cytomegalovirus
Virology, 1979Abstract Passage of human cytomegalovirus at high multiplicity of infection generated defective virus particles which banded in CsCI at a lower buoyant density than standard virus. The DNA from defective virions banded at a lower buoyant density in CsCl than standard DNA and sedimented in sucrose gradients similar to standard DNA.
M L, Ramirez +3 more
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Consequences of human cytomegalovirus mimicry
Human Immunology, 2004The HCMV genome has evolved with its host by incorporating a series of genes that are homologous to, or functionally mimic, cellular genes. Some are designed to counteract the stress of infection on the host cell, notably the viral antiapoptotic proteins (vICA, vMIA). Others potentially help the infected cell maintain a low immunologic profile.
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Overview of Human Cytomegalovirus Pathogenesis
2014Human cytomegalovirus (HCMV) is a human pathogen that infects greater than 50 % of the human population. HCMV infection is usually asymptomatic in most individuals. That is, primary infection or reactivation of latent virus is generally clinically silent.
Maciej T, Nogalski +2 more
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Construction of Recombinant Human Cytomegalovirus
2003The use of reverse genetics to generate recombinant viruses allows the researcher to investigate the exact functional significance of particular viral genes during the virus life cycle, by means of their deletion or modification in the viral genome. These studies can extend to the introduction of viral or foreign genetic material into ectopic sites in ...
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Human cytomegalovirus and immunopathology
Springer Seminars in Immunopathology, 2002J G P, Sissons +4 more
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Control of Apoptosis by Human Cytomegalovirus
2008Caspase-dependent apoptosis has an important role in controlling viruses, and as a result, viruses often encode proteins that target this pathway. Caspase-dependent apoptosis can be activated from within the infected cell as an intrinsic response to replication-associated stresses or through death-inducing signals produced extrinsically by immune cells.
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Studies on Cytomegalovirus in Human Milk
Journal of Infectious Diseases, 1983S H, Cheeseman, B R, McGraw
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Human Cytomegalovirus Infection in Transplantation
Nephron, 1993G A, Müller +3 more
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An Unbiased Screen for Human Cytomegalovirus Identifies Neuropilin-2 as a Central Viral Receptor
Cell, 2018Jessica Marcandalli +2 more
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Human cytomegalovirus elicits fetal γδ T cell responses in utero
Journal of Experimental Medicine, 2010David Vermijlen +2 more
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