Results 231 to 240 of about 34,966,316 (347)

Trends in net survival from cervical cancer in a Brazilian state with medium Human Development Index. [PDF]

Sci Rep
da Silva BEB, Di Carlo V, Minicozzi P, Ssenyonga N, Khan Baloch F, Matz M, Coleman MP, Allemani C, Lima CA.   +8 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Ecological condition of mountain lakes in the conterminous United States and vulnerability to human development. [PDF]

Ecol Indic
Handler AM, Weber M, Dumelle M, Jansen LS, Carleton JN, Schaeffer BA, Paulsen SG, Barnum T, Rea AW, Neale A, Compton JE.   +10 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Trends and patterns of global health risk factors (2015-2019): a composite index approach across 100 countries stratified by human development index groups. [PDF]

J Health Popul Nutr
Junaid KP, Kiran T, Gupta M, Kishore K, Siwatch S.   +4 more
europepmc   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

MYCN in human development and diseases. [PDF]

Front Oncol
Nishio Y, Kato K, Oishi H, Takahashi Y, Saitoh S.   +4 more
europepmc   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Toward a Unified Model of Advanced Meditation, Human Development, Meditation Maps, and Transtradition Metaphors: Facing Impermanence, Suffering, and Death. [PDF]

Mindfulness (N Y)
Sparby T, Sacchet MD.
europepmc   +1 more source