Results 71 to 80 of about 27,268,237 (302)

The Relation of Scientific Creativity and Evaluation of Scientific Impact to Scientific Reasoning and General Intelligence

open access: yesJournal of Intelligence, 2020
In many nations, grades and standardized test scores are used to select students for programs of scientific study. We suggest that the skills that these assessments measure are related to success in science, but only peripherally in comparison with two ...
Robert J. Sternberg   +3 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Athletic and sporting interests of students in the physical education classes

open access: yesPedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2013
Athletic and sporting interests of students in the physical education classes. The aim is to study the structure of sports and sporting interests and motivation for physical activities first year students.
E.O. Kosyns’kyi   +3 more
doaj  

Understanding the relationship between child stimulation and brain function using neuroimaging techniques and behavioral measures: a study protocol

open access: yesBMC Psychology
Background Cognitively stimulating environments are known to promote the intellectual, socio-emotional and language development of children. Little is known about the relation between cognition and brain structure in young children in low- and middle ...
Patricia Kitsao-Wekulo   +5 more
doaj   +1 more source

Are failures to look, to represent, or to learn associated with change blindness during screen-capture video learning?

open access: yesCognitive Research, 2018
Although phenomena such as change blindness and inattentional blindness are robust, it is not entirely clear how these failures of visual awareness are related to failures to attend to visual information, to represent it, and to ultimately learn in ...
Daniel T. Levin   +3 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Tailored antisense oligonucleotides designed to correct aberrant splicing reveal actionable groups of mutations for rare genetic disorders

open access: yesExperimental and Molecular Medicine
Effective translation of rare disease diagnosis knowledge into therapeutic applications is achievable within a reasonable timeframe; where mutations are amenable to current antisense oligonucleotide technology.
Htoo A. Wai   +7 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

The Subnational Human Development Database

open access: yesScientific Data, 2019
In this paper we describe the Subnational Human Development Database. This database contains for the period 1990–2017 for 1625 regions within 161 countries the national and subnational values of the Subnational Human Development Index (SHDI), for the ...
J. Smits, I. Permanyer
semanticscholar   +1 more source

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