Results 71 to 80 of about 27,268,237 (302)
In many nations, grades and standardized test scores are used to select students for programs of scientific study. We suggest that the skills that these assessments measure are related to success in science, but only peripherally in comparison with two ...
Robert J. Sternberg +3 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Athletic and sporting interests of students in the physical education classes
Athletic and sporting interests of students in the physical education classes. The aim is to study the structure of sports and sporting interests and motivation for physical activities first year students.
E.O. Kosyns’kyi +3 more
doaj
Background Cognitively stimulating environments are known to promote the intellectual, socio-emotional and language development of children. Little is known about the relation between cognition and brain structure in young children in low- and middle ...
Patricia Kitsao-Wekulo +5 more
doaj +1 more source
Although phenomena such as change blindness and inattentional blindness are robust, it is not entirely clear how these failures of visual awareness are related to failures to attend to visual information, to represent it, and to ultimately learn in ...
Daniel T. Levin +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Effective translation of rare disease diagnosis knowledge into therapeutic applications is achievable within a reasonable timeframe; where mutations are amenable to current antisense oligonucleotide technology.
Htoo A. Wai +7 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
The Subnational Human Development Database
In this paper we describe the Subnational Human Development Database. This database contains for the period 1990–2017 for 1625 regions within 161 countries the national and subnational values of the Subnational Human Development Index (SHDI), for the ...
J. Smits, I. Permanyer
semanticscholar +1 more source

