Results 81 to 90 of about 34,966,316 (347)

Human Development: beyond the HDI [PDF]

The well-known Human Development Index (HDI) encompasses only three rather basic aspects of human welfare. This paper aims to go beyond this, by identifying 11 categories of human development.
Gustav Ranis, Frances Stewart and Emma Samman
core   +3 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The Relation of Scientific Creativity and Evaluation of Scientific Impact to Scientific Reasoning and General Intelligence

Journal of Intelligence, 2020
In many nations, grades and standardized test scores are used to select students for programs of scientific study. We suggest that the skills that these assessments measure are related to success in science, but only peripherally in comparison with two ...
Robert J. Sternberg, Rebel J. E. Todhunter, Aaron Litvak, Karin Sternberg   +3 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Athletic and sporting interests of students in the physical education classes

Pedagogics, Psychology, Medical-Biological Problems of Physical Training and Sports, 2013
Athletic and sporting interests of students in the physical education classes. The aim is to study the structure of sports and sporting interests and motivation for physical activities first year students.
E.O. Kosyns’kyi, V.M. Khodinov, O.P. Khrypliuk, A.S. Krot   +3 more
doaj  

Understanding the relationship between child stimulation and brain function using neuroimaging techniques and behavioral measures: a study protocol

BMC Psychology
Background Cognitively stimulating environments are known to promote the intellectual, socio-emotional and language development of children. Little is known about the relation between cognition and brain structure in young children in low- and middle ...
Patricia Kitsao-Wekulo, Margaret Nampijja, Silas Onyango, Linda Oloo, Paul Otwate, Nelson Langat   +5 more
doaj   +1 more source

Are failures to look, to represent, or to learn associated with change blindness during screen-capture video learning?

Cognitive Research, 2018
Although phenomena such as change blindness and inattentional blindness are robust, it is not entirely clear how these failures of visual awareness are related to failures to attend to visual information, to represent it, and to ultimately learn in ...
Daniel T. Levin, Adriane E. Seiffert, Sun-Joo Cho, Kelly E. Carter   +3 more
doaj   +1 more source

Maximizing Human Development [PDF]

The Human Development Index (HDI) is widely used as an aggregate measure of overall human well being. We examine the allocations implied by the maximization of this index, using a standard growth model — an extended version of Mankiw, Romer, andWeil’s ...
Ian King, Merwan Engineer
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Tailored antisense oligonucleotides designed to correct aberrant splicing reveal actionable groups of mutations for rare genetic disorders

Experimental and Molecular Medicine
Effective translation of rare disease diagnosis knowledge into therapeutic applications is achievable within a reasonable timeframe; where mutations are amenable to current antisense oligonucleotide technology.
Htoo A. Wai, Eliska Svobodova, Natalia Romero Herrera, Andrew G. L. Douglas, John W. Holloway, Francisco E. Baralle, Marco Baralle, Diana Baralle   +7 more
doaj   +1 more source