Results 121 to 130 of about 597,824 (308)

Розвиток ідей Сергія Подолинського у працях Алекса Подолинського [PDF]

open access: yes
Alex Podolynsky irealizes in practice new ecologic and economic paradigm by Sergii Podolynskyi containing the humanity development strategy with energy conservation and accumulation on Earth.
Грицай, М. П.
core   +1 more source

Environmental and consumer safety of goods and services [PDF]

open access: yes, 2007
The problem of safety is one of global human problems which directly concerns with survival of humanity. It has a system property and that is why it requires the examination from different sides of different sciences such as politics, economics ...
Linnik, Yuliya
core  

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Transhumanism as an intellectual and technological paradigm of future medicine: Opportunities and threats

open access: yesRussian Studies in Culture and Society
Background. Throughout its history, humanity has faced serious challenges, from the question of death to those associated with the development of artificial intelligence.
Elena A. Smirnova
doaj   +1 more source

The contemporary challenges facing college of education students as future educational leaders at Sultan Qaboos University from their view points : Survey study [PDF]

open access: yes, 2007
The contemporary challenges of young people are matter of high priority, and one of the crucial issues since they are considered as a major part of human capital in Arab States and over the entire world.
Al-Ani, Wajeha Thabit
core  

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Global factors which influence the directions of social development [PDF]

open access: yes, 2017
This study identifies global factors conditioning the global problematics of the direction of social development. Global threats were evaluated and defined as dangerous processes, phenomena, and situations that cause harm to health ...
S. Sardak, M. Korneyev, A. Simakhova, O. Bilskaya   +1 more
core  

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Human Development Report 1991: Financing Human Development [PDF]

open access: yes, 1991
Lack of political commitment rather than financial resources is often the real barrier to human development. This is the main conclusion of Human Development Report 1991 - the second in a series of annual reports on the subject.
openaire  

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