Results 131 to 140 of about 2,108,756 (374)

The Modern Idea of Progress by Jean A. Condorcet [PDF]

open access: yesStudia Warmińskie, 2017
The 18th century is the opening to cognitive progress (epistemology) which becomes the core of historical progress. They were defined more precisely by Robert Turgot (1727-1781).
Podgórski Ryszard
doaj  

Bioethics: Reincarnation of Natural Philosophy in Modern Science [PDF]

open access: yes, 2017
The theory of evolution of complex and comprising of human systems and algorithm for its constructing are the synthesis of evolutionary epistemology, philosophical anthropology and concrete scientific empirical basis in ...
Cheshko, Valentin Teodorovich   +2 more
core  

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

THE THEORY OF CIVILIZATIONS THROUGH THE LENS OF CONTEMPORARY HUMANITIES

open access: yesAntropologìčnì Vimìri Fìlosofsʹkih Doslìdžen', 2016
Purpose. This paper invites reflections on the further development of civilizational theory through the lens of contemporary humanities. It argues that philosophy is one of the key dimensions of the integral theory of civilizations.
T. V. Danylova
doaj   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

The ethical problem of Kant's cosmic peace

open access: yesآداب الكوفة, 2012
There is no hope that man seeks in our world and our time and longs for with passion, more than what he longs for in eternal and cosmic peace, a peace that would liberate the future of humanity from its greatest suffering resulting from the rapid ...
سمير بلكفيف
doaj   +2 more sources

A Participatory Universe of J. A. Wheeler as an Intentional Correlate of Embodied Subjects and an Example of Purposiveness in Physics [PDF]

open access: yes, 2013
This paper investigates the role of human subjectivity and its delimiters in articulating the universe in physics and cosmology. As a case study, we reflect upon the complex of ideas of the so called Participatory Universe by later J. A. Wheeler.
Nesteruk, Alexei V.
core   +1 more source

Antigen identification strategies and preclinical evaluation models for advancing tuberculosis vaccine development

open access: yesnpj Vaccines
In its myriad devastating forms, Tuberculosis (TB) has existed for centuries, and humanity is still affected by it. Mycobacterium tuberculosis ( M. tuberculosis ), the causative agent of TB, was the foremost killer among infectious agents until the COVID-
Saurabh Chugh   +3 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

From Nuremberg to Rome and Beyond: The Fight Against Genocide, War Crimes, and Crimes Against Humanity [PDF]

open access: yes, 1999
More than 200 years ago in his work Perpetual Peace, \u27 Immanuel Kant called for peace and human rights to be protected under international law. Ever since, the United Nations, which was founded in 1945 as part of the worldwide fight against tyranny ...
Kastrup, Dieter
core   +1 more source

Home - About - Disclaimer - Privacy