Results 121 to 130 of about 5,315,351 (390)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Territorial Differences of Human Development Index in Romania [PDF]
Romanian Review of Regional Studies, 2011 The measuring of human capital, human development from both a quantitative and a qualitative point of view is difficult, the problem being further complicated if we consider regional and territorial approaches as well.
IBOLYA KURKÓ
doaj
The Spatial Dimension of Human Development Index in Indonesia [PDF]
As the new paradigm of economic development pioneered by UNDP and Mahbub Ul-Haq undertaken, development processes no longer viewed as monodimensional process of economic growth indicated by GDP growth solely.
Eva Nurwita, Rullan Rinaldi
core
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
American Journal of Business Science PhilosophyThis study critically examines the impact of International Non-Government Organizations’ (INGOs) educational funding on human development outcomes in conflict-affected and developing regions, focusing on Syria, Bangladesh, DRC, Sudan, and Ukraine ...
Ali Asaad, Masatoshi Hara
doaj +1 more source
Вектор соціального розвитку України в контексті перспектив побудови інноваційної економіки
, 2014 The article is devoted to the problems of social and human development in the context of transformation of modern economy into innovative one. Theoretical analysis of the main directions of human development have been carried out.
Semykina, Anna +1 more
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Analisis Pengaruh Pertumbuhan Ekonomi , Kemiskinan Dan Pengangguran Terhadap Indeks Pembangunan Manusia (IPM) Di Wilayah Subosukawonosraten [PDF]
, 2016 Human development is a process of development that aims to be able to have more choices, particularly in income, health and education. One criterion can be seen through the Human Development Index.
, Ir. Maulidyah Indira Hasmarini, MS. +1 more
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Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Measuring human and Sustainable Development: An Integrated Approach for European Countries [PDF]
During the last few years, sustainable development has represented one of the most important policy goals at global level and how to design specific policy actions, measuring performance and results continues to present a challenge.
Salvatore Monni, Valeria Costantini
core
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source