Results 201 to 210 of about 25,111,230 (304)

Beliefs and Barriers to COVID-19 Vaccine Acceptance in Three Countries with Different Human Development Index (HDI) Scores: A Comparative Study. [PDF]

Patient Prefer Adherence, 2022
Makki S, Siddiqua A, Wahab S, Siddiqui S, Faheemuddin M, Abobaker I, Abdelmoniem A, Khaled A.   +7 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

A Human Development Index by Internal Migration Status [PDF]

Migration continues to be a very important income diversification strategy, especially for poor populations in developing countries. However, while there has been much analysis on the economic consequences of migration for migrants and the receiving ...
Stephan Klasen, Kenneth Harttgen
core  

Vaccination Coverage Against Coronavirus Disease 2019 in People Living on Quilombos in Brazil and Its Association With the Human Development Index and the Quality of the Health System. [PDF]

J Med Virol
Costa PT, Mello LS, Marques LFA, Dos Santos VS, Marson FAL.   +4 more
europepmc   +1 more source

Correlation between human development index and its components with COVID-19 indices: a global level ecologic study. [PDF]

BMC Public Health, 2022
Mirahmadizadeh A, Ghelichi-Ghojogh M, Vali M, Jokari K, Ghaem H, Hemmati A, Jafari F, Dehghani SS, Hassani AH, Jafari A, Rezaei F.   +10 more
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The COVID-19 health emergency: the influence of the Human Development Index on the reorganization of primary care. [PDF]

Front Public Health
Corrêa APV, Ribeiro AC, Cano RDN, Magno GD, Álvarez-Nieto C, Uehara SCDSA.   +5 more
europepmc   +1 more source

Lip and Oral Cavity Cancer Incidence and Mortality Rates Associated with Smoking and Chewing Tobacco Use and the Human Development Index in 172 Countries Worldwide: An Ecological Study 2019-2020. [PDF]

Healthcare (Basel), 2023
Hernández-Morales A, González-López BS, Scougall-Vilchis RJ, Bermeo-Escalona JR, Velázquez-Enríquez U, Islas-Zarazúa R, Márquez-Rodríguez S, Sosa-Velasco TA, Medina-Solís CE, Maupomé G.   +9 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Global and regional trends in under-five diarrheal disease burden: impact of human development index and geographic disparities, 1990-2021. [PDF]

Gastroenterol Hepatol Bed Bench
Azizmohammad Looha M, Saberi Shahrbabaki A, Mohammadpoor A, Zamani M, Sadeghloo Z, Jameie M, Mousavi H, Pooresmaeil Niaki SR, Mohebbi H, Asadimanesh N, Norouzi F, Banar S, Jalalinejad M, Yousefi M, Shahreki Mojahed S, Masheghati F, Ghalandarlaki M, Bahadorimonfared A.   +17 more
europepmc   +1 more source