Results 221 to 230 of about 3,317,170 (346)

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Global and regional trends in under-five diarrheal disease burden: impact of human development index and geographic disparities, 1990-2021. [PDF]

Gastroenterol Hepatol Bed Bench
Azizmohammad Looha M, Saberi Shahrbabaki A, Mohammadpoor A, Zamani M, Sadeghloo Z, Jameie M, Mousavi H, Pooresmaeil Niaki SR, Mohebbi H, Asadimanesh N, Norouzi F, Banar S, Jalalinejad M, Yousefi M, Shahreki Mojahed S, Masheghati F, Ghalandarlaki M, Bahadorimonfared A.   +17 more
europepmc   +1 more source

Association between Suicide Rate and Human Development Index, Income, and the Political System in 46 Muslim-Majority Countries: An Ecological Study. [PDF]

Eur J Investig Health Psychol Educ, 2022
Arafat SMY, Marthoenis M, Khan MM, Rezaeian M.   +3 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Human Development and Economic Uncertainties: Exploring Another Dimension of Development

Lahore Journal of Economics
This study makes the case that economic uncertainties—i.e., the extent to which economies face systemic uncertainties—need to be considered another dimension of human development because they render development vulnerable, diminish social welfare, and ...
Jamshed Y. Uppal, Syeda Rabab Mudakkar
doaj  

Correction: Burden of type 2 diabetes and its relationship with human development index in Asian countries: Global Burden of Disease Study in 2019. [PDF]

BMC Public Health
Alinaghian SA, Hamidzadeh S, Badrizadeh A, Khazaei Z, Souri A, Momenabadi V, Goodarzi E.   +6 more
europepmc   +1 more source

Relationship between socio-demographic correlates and human development index with physical activity and sedentary time in a cross-sectional multicenter study. [PDF]

BMC Public Health, 2022
Ferrari G, Farías-Valenzuela C, Guzmán-Habinger J, Drenowatz C, Marques A, Kovalskys I, Gómez G, Rigotti A, Cortés LY, Yépez García MC, Pareja RG, Herrera-Cuenca M, Marconcin P, Chávez JL, Fisberg M.   +14 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Disparities in wellbeing in the USA by race and ethnicity, age, sex, and location, 2008-21: an analysis using the Human Development Index. [PDF]

Lancet
Dwyer-Lindgren L, Kendrick P, Baumann MM, Li Z, Schmidt C, Sylte DO, Daoud F, La Motte-Kerr W, Aldridge RW, Bisignano C, Hay SI, Mokdad AH, Murray CJL.   +12 more
europepmc   +1 more source

Correlation between COVID-19 vaccination coverage and human development index

, 2023
Rezaei F, Vali M, Aune D.
europepmc   +1 more source