Results 111 to 120 of about 831,336 (352)

Human-Induced Disturbance Alters Pollinator Communities in Tropical Mountain Forests

open access: yesDiversity, 2012
Mountain forest ecosystems in the Andes are threatened by deforestation. Increasing fire frequencies lead to fire-degraded habitats that are often characterized by a persistent fern-dominated vegetation.
Matthias Schleuning   +4 more
doaj   +1 more source

Human Disturbance Influences Occupancy of Red Deer in Mongolia

open access: diamond, 2022
Rhiannon Henderson   +4 more
openalex   +2 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

What does the fox select? Spatial ecology of Rocky Mountain red fox during peaks and troughs of human recreation

open access: yesEcosphere
Understanding animal behavior at the population level can be challenging, especially in the presence of intraspecific variation in behavioral tactics. Individuals within a population often vary with respect to resource exploitation and use, which may be ...
Emily N. Burkholder   +4 more
doaj   +1 more source

Habituation reverses fear‐based ecological effects in brown bears (Ursus arctos)

open access: yesEcosphere, 2016
Fear induced by human activity is increasingly becoming recognized to influence both behavior and population biology of wildlife. Exposure to human activity can cause animals to avoid human‐dominated areas or shift temporal activity patterns, but ...
Rachel E. Wheat, Christopher C. Wilmers
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

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