Results 61 to 70 of about 17,528,888 (291)
, 2018 Some well-known scientists and technologists have expressed concern that robots may take over the world. More generally, there is concern that robots will take over human jobs and leave billions of people suffering long-term unemployment.
S. Fox
semanticscholar +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome
Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja +8 more
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Cognitive enhancement. Effort of definition, and methods [PDF]
Avant, 2015 The idea of cognitive enhancement refers to multifaceted and interdisciplinary approach aimed at improving human mental processes. Cognitive enhancement is the amplification or extension of core mind capacities through improvement or augmentation of ...
Artur Gunia
doaj
Cognitive Enhancement in Humans [PDF]
, 2015 Contains fulltext : 237623.pdf (Publisher’s version ) (Open Access)
Dresler, M., Repantis, D.
openaire +2 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Materials Today BioHypoxia and electron-hole recombination are two obstacles limiting sonodynamic therapeutic efficacy against cancer. Herein, bismuth sulfide (Bi2S3)-titania (TiO2) heterostructure is designed based on the excellent photothermal property of Bi2S3, which ...
Rui Chen +11 more
doaj +1 more source
Understanding human enhancement technologies through critical phenomenology
Nursing Philosophy, 2018 Human enhancement technologies raise serious ethical questions about health practices no longer content simply to treat disease, but which now also propose to "optimize" human beings' physical, cognitive and psychological abilities.
Pierre Pariseau-Legault +2 more
semanticscholar +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
FEBS Letters, EarlyView.CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source