Results 81 to 90 of about 606,320 (250)

The pyruvate generator is a common phenomenon in mitochondria from different rat and mouse brain regions

open access: yesFEBS Letters, EarlyView.
The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber   +7 more
wiley   +1 more source

THE THEOLOGICAL DEBATE OVER HUMAN ENHANCEMENT: AN EMPIRICAL CASE STUDY OF A MEDIATING ORGANIZATION

open access: yesZygon, 2020
For most theologians, theology should ultimately be used by the laity and/or the public. However, the religion and science debate has not focused on the divide between theologians and the laity.
doaj   +2 more sources

Geneticizing Ethnicity and Diet: Anti-doping Science and Its Social Impact in the Age of Post-genomics

open access: yesFrontiers in Genetics, 2017
While gene doping and other technological means of sport enhancement have become a topic of ethical debate, a major outcome from genomic research in sports is often linked to the regulation of doping.
Jaehwan Hyun
doaj   +1 more source

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

In Support of Human Enhancement [PDF]

open access: yesStudies in Ethics, Law, and Technology, 2008
Chan, S., Harris, J.
openaire   +3 more sources

Sexual dimorphism and human enhancement [PDF]

open access: yesJournal of Medical Ethics, 2012
Robert Sparrow argues that because of women's longer life expectancy philosophers who advocate the genetic modification of human beings to enhance welfare rather than merely supply therapy are committed to favouring the selection of only female embryos, an implication he deems sufficiently implausible to discredit their position.
openaire   +2 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Conceptual Origins of the Transhumanist Paradigm in the Alchemical Tradition

open access: yesRUDN Journal of Philosophy
This work analyzes alchemical doctrine through the lens of ideas that correlate with the theoretical constructs of transhumanism. It is shown that alchemy, a complex and contradictory cultural phenomenon that existed in various civilizations over long ...
Ekaterina N. Gnatik
doaj   +1 more source

Life extension: a biomedical goal?

open access: yesSwiss Medical Weekly, 2011
The potential for development of biomedical technologies capable of extending the human lifespan raises at least two kinds of question that it is important both to distinguish and to connect with one another: scientific, factual questions regarding the
G Barazzetti, M Reichlin
doaj   +1 more source

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