Results 81 to 90 of about 652,882 (295)
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Moral Enhancement and the Human Condition [PDF]
, 2019 This is the author accepted manuscript. The final version is available from Cambridge University PressThe papers collected in this volume examine moral enhancement: the idea that we should morally improve people through the manipulation of their ...
Skidelsky, E
core
Visual enhancement of touch and the bodily self [PDF]
, 2008 We experience our own body through both touch and vision. We further see that others’ bodies are similar to our own body, but we have no direct experience of touch on others’ bodies.
Longo, Matthew R. +2 more
core +1 more source
Lip print enhancement: review [PDF]
, 2020 Lip print (LP) evidence can be an essential tool for human forensics. LPs have conventionally been developed using substances such as lysochrome dyes, fluorescent dyes, indigo dye, aluminium powder, and silver metallic powder.
Abedi, Maxwell +2 more
core +1 more source
Journal of Health Science and Medical Research (JHSMR)Objective: To translate and culturally adapt the Updated Perceived Control Over Falling (UP-COF) into the Thai language and evaluate its psychometric properties among older Thai adults.
Kanjanaporn Tantrongphak +2 more
doaj +1 more source
Colloquia Theologica Ottoniana, 2020 Niniejsza praca jest recenzją książki "Ulepszanie człowieka. Perspektywa filozoficzna" (pod. red. G. Hołuba i P. Duchlińskiego, Wydawnictwo Naukowe Akademii Ignatianum w Krakowie, Kraków 2018).
Marcin Ferdynus
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The why's the limit: curtailing self-enhancement with explanatory introspection [PDF]
, 2007 Self-enhancement is linked to psychological gains (e.g., subjective well-being, persistence in adversity) but also to intrapersonal and interpersonal costs (e.g., excessive risk taking, antisocial behavior).
Sedikides, Constantine +2 more
core +1 more source
A Quest for the Essence of Human Enhancement
Yixue yu zhexueHuman enhancement refers to the practical operation and application of relevant technologies on human beings (including the physiological, cognitive, emotional and willpower dimensions), and thereby extending, replacing or updating all aspects of the ...
Xuan JIANG
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source