Results 101 to 110 of about 18,710,371 (326)

Human enhancement: questioni biogiuridiche

open access: yesInternational Journal of Developmental and Educational Psychology. Revista INFAD de Psicología., 2019
Human Enhancement is a modification aimed to improve human’s characteristics and capabilities through scientific or technological interventions in the human body, starting from an ‘integrity condition’ and not from a state of disease. Therefore, we need to value if the enhancement is harmful of the human dignity or if it’s an useful tool to improve the
lidia ricci   +2 more
openaire   +3 more sources

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Reframing Human Enhancement: A Population Health Perspective

open access: yesFrontiers in Sociology, 2017
The dominant understandings on human enhancement, such as those based on the therapy-enhancement distinction or transhumanist views, have been focused on high technological interventions directly changing biological and physical features of individuals ...
L. Cabrera
semanticscholar   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Human enhancement: from disability to superability [PDF]

open access: yesDevelopmental Medicine & Child Neurology, 2019
Video Podcast: https://www.youtube.com/watch?v=GY9YmA2jkow&t ...
openaire   +2 more sources

Political Minimalism and Social Debates: The Case of Human-Enhancement Technologies

open access: yesJournal of Bioethical Inquiry, 2017
A faulty understanding of the relationship between morality and politics encumbers many contemporary debates on human enhancement. As a result, some ethical reflections on enhancement undervalue its social dimensions, while some social approaches to the ...
J. Rodríguez-Alcázar
semanticscholar   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Knowledge management: Exploring the relationship between human capital and organisation structure capital [PDF]

open access: yes, 2010
Human capital and its impact on the organisation structure capital are of paramount importance in the modern business organisations. This research in progress, which investigates and analyses the role that human capital plays in the determination of the ...
Al-Halak, A   +3 more
core  

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

SARS CoV subunit vaccine: Antibodymediated neutralisation and enhancement [PDF]

open access: yes, 2012
1. A SARS vaccine was produced based on recombinant native full-length Spike-protein trimers (triSpike) and efficient establishment of a vaccination procedure in rodents. 2.
Altmeyer, R   +14 more
core   +1 more source

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