Results 91 to 100 of about 606,320 (250)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Humana.Mente: Journal of Philosophical Studies, 2014 The expression “human enhancement” could be placed in the ontological, cognitive, and symbolic dimension in which we conceive and experience the faculty, that is constitutive of human beings, of giving name and thus consistence to things, relations and ...
Barbara Henry
doaj
Detection of Rehabilitation Training Effect of Upper Limb Movement Disorder Based on MPL-CNN
SensorsStroke represents a medical emergency and can lead to the development of movement disorders such as abnormal muscle tone, limited range of motion, or abnormalities in coordination and balance. In order to help stroke patients recover as soon as possible,
Lijuan Shi +4 more
doaj +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
On the (Non-)Rationality of Human Enhancement and Transhumanism. [PDF]
Sci Eng Ethics, 2022 Lyreskog DM, McKeown A.
europepmc +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Is human enhancement intrinsically bad? [PDF]
Med Health Care Philos, 2021 Kudlek K.
europepmc +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Transhumanism and its Genesis: The Shaping of Human Enhancement Discourse by Visions of the Future
Humana.Mente: Journal of Philosophical Studies, 2014 Current discourse on human enhancement is strongly influenced by far-reaching, radical visions concerning the future of human corporeality and civilisation.
Christopher Coenen
doaj
Acta PsychologicaTo our knowledge, few studies have attempted to explore the social perception of targets engaged in performance enhancement and body modification, and none has done so through a systematic review and meta-analysis.
Hailemariam Weldemariam +5 more
doaj +1 more source