Results 121 to 130 of about 9,181,875 (263)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Human enhancement drugs and new(?) research directions

open access: yes, 2020
Human enhancement drugs and new(?) research ...
K Mulrooney (13505839)   +2 more
core  

Anthropological Arguments in the Ethical Debate about Human Enhancement

open access: yesHumana.Mente: Journal of Philosophical Studies, 2014
The paper discusses the role of anthropological arguments in contemporary ethics as exemplified in the current debate about biotechnological human enhancement interventions. Anthropological arguments refer to a normative conception of what it means to be
Jan-Christoph Heilinger
doaj  

Eyes and movement differences in unconscious state during microscopic procedures

open access: yesScientific Reports
Microsurgery is one of the techniques that is increasingly being adopted in many surgical fields. However, the acquisition and transfer of microsurgical skills primarily depend on experience.
Akiko Fujita   +6 more
doaj   +1 more source

Post genetic revolution dynamics. How will modified and unmodified humans coexist?

open access: yesEnrahonar: Quaderns de Filosofia
In this article I claim that the genetic revolution, that is, the advent of a series of highly transformative and disruptive genetic technologies, will happen in the coming years. Given the importance of this historical event, I argue that we must think
Marcos Alonso
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Genetic Enhancement, Technological Objectification, and Heidegger's Gelassenheit

open access: yes
This article combines the works of Nussbaum, Habermas, and Heidegger in a critique of non-therapeutic genome editing for human enhancement. The objections presented by Habermas in his The Future of Human Nature are extended and strengthened.
Crowden, Andrew, Gildersleeve, Matthew
core   +1 more source

Towards a “Human Enhancement Society”? Opportunities for an Aristotelian Approach to Frame the Question

open access: yesHumana.Mente: Journal of Philosophical Studies, 2014
The essay is subdivided into three parts. In the first and introductory one the current debate on human enhancement is presented, with specific reference to its interdisciplinary characteristics and to the aspects which explicitly challenge “the human ...
Alberto Pirni
doaj  

A novel logarithmic spiral design for proximal interphalangeal joint arthroplasty

open access: yesScientific Reports
This study evaluated a novel implant for proximal interphalangeal (PIP) joint arthroplasty that we designed according to the principles of a logarithmic spiral. The design addresses the limitations of current implants that poorly replicate natural finger
Hitoshi Hirata   +5 more
doaj   +1 more source

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