Results 131 to 140 of about 652,882 (295)

The social perception of performance enhancement and body modification: A systematic review and meta-analysis on anabolic steroids, tattoos, and cosmetic surgery

open access: yesActa Psychologica
To our knowledge, few studies have attempted to explore the social perception of targets engaged in performance enhancement and body modification, and none has done so through a systematic review and meta-analysis.
Hailemariam Weldemariam   +5 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Human enhancement ed identità genetica dell’embrione

open access: yesEuropean Journal of Privacy Law & Technologies
Gli interventi di editing genetico eseguiti con la tecnica CRISPR-Cas9 aprono a scenari migliorativi per la salute umana, ma presentano criticità non trascurabili, a partire dalle definizioni giuridiche di salute e malattia, fino alla configurabilità ...
Francesca Ferretti
doaj   +1 more source

Vaccination against SARS-CoV-2: a human enhancement story. [PDF]

open access: yesTransl Med Commun, 2021
Döbler NA, Carbon CC.
europepmc   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Eyes and movement differences in unconscious state during microscopic procedures

open access: yesScientific Reports
Microsurgery is one of the techniques that is increasingly being adopted in many surgical fields. However, the acquisition and transfer of microsurgical skills primarily depend on experience.
Akiko Fujita   +6 more
doaj   +1 more source

Post genetic revolution dynamics. How will modified and unmodified humans coexist?

open access: yesEnrahonar: Quaderns de Filosofia
In this article I claim that the genetic revolution, that is, the advent of a series of highly transformative and disruptive genetic technologies, will happen in the coming years. Given the importance of this historical event, I argue that we must think
Marcos Alonso
doaj   +1 more source

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