Results 131 to 140 of about 871,311 (264)

The planetary diet: a nutritional utopia in conflict with human evolution. [PDF]

Nutr Metab (Lond)
Spinosa JP, Lee DC, Duraj T, Seyfried TN.   +3 more
europepmc   +1 more source

A Catalog of Coding Sequence Variations in Salivary Proteins' Genes Occurring during Recent Human Evolution. [PDF]

Int J Mol Sci, 2023
Di Pietro L, Boroumand M, Lattanzi W, Manconi B, Salvati M, Cabras T, Olianas A, Flore L, Serrao S, Calò CM, Francalacci P, Parolini O, Castagnola M.   +12 more
europepmc   +1 more source

Principles of Human Evolution [PDF]

Journal of Evolutionary Biology, 1999
openaire   +2 more sources

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Global impact of micronutrients in modern human evolution. [PDF]

Am J Hum Genet
Rees J, Castellano S, Andrés AM.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Evolving a Field: Can Evolutionary Theory Provide What the Study of Human Evolution Requires? [PDF]

Am J Biol Anthropol
Roseman CC, Auerbach BM.
europepmc   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

Molecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak, Iva Staniczková Zambo, Matěj Přikryl, Peter Múdry, Danica Zapletalová, Jarmila Navrátilová, Jiří Navrátil, Jan Šmarda, Liudmyla Drobot, Petr Beneš, Lucia Knopfová   +10 more
wiley   +1 more source

The genetic architecture of human cerebellar morphology supports a key role for the cerebellum in human evolution and psychopathology. [PDF]

Commun Biol
Moberget T, van der Meer D, Bahrami S, Roelfs D, Frei O, Kaufmann T, Fernandez-Cabello S, Kim M, Wolfers T, Diedrichsen J, Smeland OB, Shadrin A, Dale A, Andreassen OA, Westlye LT.   +14 more
europepmc   +1 more source

The Price of Human Evolution: Cancer-Testis Antigens, the Decline in Male Fertility and the Increase in Cancer. [PDF]

Int J Mol Sci, 2023
Erenpreisa J, Vainshelbaum NM, Lazovska M, Karklins R, Salmina K, Zayakin P, Rumnieks F, Inashkina I, Pjanova D, Erenpreiss J.   +9 more
europepmc   +1 more source