Results 131 to 140 of about 208,116 (260)

The future of fundamental science led by generative closed-loop artificial intelligence. [PDF]

Front Artif Intell
Zenil H, Tegnér J, Abrahão FS, Lavin A, Kumar V, Frey JG, Weller A, Soldatova L, Bundy AR, Jennings NR, Takahashi K, Hunter L, Dzeroski S, Briggs A, Gregory FD, Gomes CP, Rowe J, Evans J, Kitano H, King R.   +19 more
europepmc   +1 more source

Nationwide Survey of Patient Knowledge and Attitudes towards Human Experimentation Using Stem Cells or Bee Venom Acupuncture for Parkinson's Disease. [PDF]

J Mov Disord, 2014
Korean Movement Disorders Society Red Tulip Survey Participants, Chung SJ, Koh SB, Ju YS, Kim JW.   +4 more
europepmc   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

LINA's testing infrastructure enables AI to take-off in unmanned aerial vehicles (UAVs). [PDF]

Front Robot AI
Bolck HA, Vollenweider J, Merkli F, Barden A, Jajcay M, Trempeck P, Rafailović B, Fraefel R, Lenhart PM, Chavarriaga R, Renold M, Bogojeska J, Stadelmann T, Guillaume M.   +13 more
europepmc   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

Reframing chemistry education in the age of automation and AI. [PDF]

Commun Chem
G Kurth D.
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Development of a High-Throughput Experimentation Workflow for Photochemical Reaction Screening. [PDF]

ACS Med Chem Lett
Nguyen N, Masui C, Childs A, Barlow A, Chen T, Huestis MP.   +5 more
europepmc   +1 more source