Results 151 to 160 of about 207,063 (262)

Profound cell wall remodeling in <i>Candida parapsilosis</i> during systemic infection confers simultaneous tolerance to echinocandins and host immunity. [PDF]

Microbiol Spectr
Daneshnia F, Cai L, Gunasekaran D, Gautam I, Perry AM, Mosharaf Ghahfarokhy P, Ebadati A, Munoz J, Padilla D, Hilmioglu-Polat S, Mei S, Floyd DJ, Schikora-Tamarit MÀ, Fuentes D, Artigues-Lleixà M, Walker LA, Gonçalves SM, Salehi M, Carvalho A, Desai JV, Perlin DS, Munro CA, Hopke A, Wang T, Gabaldón T, Fang W, Nobile CJ, Mansour MK, Arastehfar A.   +28 more
europepmc   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source

From safer alternative to public health crisis: the unintended consequences of e-cigarettes. [PDF]

Ann Med Surg (Lond)
Ahmed SS, Ahmed F, Qureshi AG, Raza AA, Samadi A.   +4 more
europepmc   +1 more source

Nationwide Survey of Patient Knowledge and Attitudes towards Human Experimentation Using Stem Cells or Bee Venom Acupuncture for Parkinson's Disease. [PDF]

J Mov Disord, 2014
Korean Movement Disorders Society Red Tulip Survey Participants, Chung SJ, Koh SB, Ju YS, Kim JW.   +4 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Autonomous microfluidic labs: progress and prospects.

Lab Chip
Damir S, Delgado-Licona F, deMello A, Abolhasani M.   +3 more
europepmc   +1 more source

Making sense together: participatory sensemaking, learning cycles, and group roles. [PDF]

Front Psychol
Kronsted C, Henley M, Giguere M.
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Advancing the 3Rs in bone tissue engineering: emerging <i>in vitro</i>, <i>in silico</i>, and refined <i>in vivo</i> strategies. [PDF]

Front Physiol
Cagle AL, Limberg AK, Anup A, La Croix AE, Hixon KR.   +4 more
europepmc   +1 more source