Results 201 to 210 of about 183,921 (244)

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

A Position Paper on ’Living Laboratories’: Rethinking Ecological Designs and Experimentation in Human-Computer Interaction

, 2009
Ed H.
openalex   +1 more source

Self-Reflective Practice, Autoethnography, Storytelling, and Critical Incident Analysis in Exploratory Nursing and Midwifery Research: Facing Social Illnesses and Borderline Personality Disorder. [PDF]

Iran J Nurs Midwifery Res
Lazzari C, Nikolou-Walker E, Liu L.
europepmc   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

FEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna, Richard Buchal, Martin Leníček, Amit Shachak, Jan Pláteník   +4 more
wiley   +1 more source

How To Become a Top Model: Impact of Animal Experimentation on Human Salmonella Disease Research

, 2011
Renée M. Tsolis, Mariana N. Xavier, Renato L. Santos, Andreas J. Bäumler   +3 more
openalex   +1 more source

Mercury poisoning in women and infants inhabiting the Gangetic plains of Bihar: risk assessment. [PDF]

BMC Public Health
Kumar A, Agarwal R, Kumar K, Chayal NK, Kumar G, Kumar R, Ali M, Srivastava A, Aryal S, Pandey T, Verma KS, Kumar D, Gajbhiye RL, Dhingra S, Pothuraju N, Peraman R, Bishwapriya A, Nandan R, Sharma A, Singh M, Ghosh AK.   +20 more
europepmc   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

The 8-fold quadrant dissection method for ex vivo human interventional retinal experimentation

, 2017
Aparna Murali, Charmaine A. Ramlogan‐Steel, Sławomir Andrzejewski, Bijay Dhungel, Jason C. Steel, Christopher J. Layton   +5 more
openalex   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source