Results 191 to 200 of about 18,923,181 (308)

Functional connectivity changes in the brain following 40 Hz noninvasive brain stimulation protocols with iTBS and tACS

Brain Stimulation
Mohammad Ali Salehinejad, Benedikt Glinski, Kiomars Sharifi, Min-Fang Kuo, Michael Nitsche   +4 more
doaj   +1 more source

Exploring human factors that affect patient safety in dentistry: a qualitative study of hospital-based practice. [PDF]

BMC Oral Health
Siddiqui M, Younis MA, Fahim A, Bashir U, Ayub F, Jehangir A.   +5 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Exploring alarm fatigue among clinical nurses through a human factors engineering framework: a descriptive qualitative study. [PDF]

Front Public Health
Liu Y, Zhang J, Zhang Z, Tian L, Wang P.
europepmc   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Occupational safety in coal logistics: a systematic review of systemic risks and human factors. [PDF]

Front Public Health
Abdullah WPAW, Arifin K, Juhari ML, Aiyub K, Abas A.   +4 more
europepmc   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Rehabilitation strategies for long COVID: integrating human factors engineering. [PDF]

Front Rehabil Sci
Hung TS.
europepmc   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Nozzle Angle Optimization for Nasopharyngeal Drug Delivery: In Vitro Penetration Testing and Human Factors Usability Validation. [PDF]

Cureus
Alas-Pineda C, Hasan Akash MM, Malakar A, Coto-Tejeda C, Medina-Mejía J, Pavón-Varela DJ, Gaitán-Zambrano K, Ferrer G, Basu S.   +8 more
europepmc   +1 more source