Studying Human Fertility [PDF]
We very much welcome the National Children’s Study, which promises to raise the study of factors affecting reproduction and development to a new level. An impressive and exciting range of new methodologies is being developed (Chapin and Buck 2004; National Children’s Study 2004).
Jane Key+3 more
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Regulated mitochondrial DNA replication during oocyte maturation is essential for successful porcine embryonic development. [PDF]
Cellular ATP is mainly generated through mitochondrial oxidative phosphorylation, which is dependent on mitochondrial DNA (mtDNA). We have previously demonstrated the importance of oocyte mtDNA for porcine and human fertilization.
Alexander, Jan+26 more
core +7 more sources
Fertilization Narratives In The Art Of Gustav Klimt, Diego Rivera And Frida Kahlo: Repression, Domination And Eros Among Cells [PDF]
Fertilization narratives are powerful biological stories that can be used for social ends, and 20th-century artists have used fertilization-based imagery to convey political and social ideas.
Brauckmann, S., Gilbert, Scott F.
core +2 more sources
Human sperm ion channel (dys)function:implications for fertilization [PDF]
BACKGROUND: Intensive research on sperm ion channels has identified members of several ion channel families in both mouse and human sperm. Gene knock-out studies have unequivocally demonstrated the importance of the calcium and potassium conductances in ...
Barratt, Christopher L. R.+3 more
core +3 more sources
Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF [PDF]
STUDY QUESTION. Are significant abnormalities in outward (K+) conductance and resting membrane potential (Vm) present in the spermatozoa of patients undertaking IVF and ICSI and if so, what is their functional effect on fertilization success?
Barratt, Christopher L. R.+9 more
core +6 more sources
Derivation of HVR1, HVR2 and HVR3 human embryonic stem cell lines from IVF embryos after preimplantation genetic diagnosis (PGD) for monogenic disorder [PDF]
From 106 human blastocyts donate for research after in vitro fertilization (IVF) and preimplantation genetic diagnosis (PGD) for monogenetic disorder, 3 human embryonic stem cells (hESCs) HVR1, HVR2 and HVR3 were successfully derived.
Aguilera, Yolanda+9 more
core +2 more sources
Involvement of sperm acetylated histones and the nuclear isoform of Glutathione peroxidase 4 in fertilization [PDF]
We previously demonstrated that the nuclear form of Glutathione peroxidase 4 (nGPx4) has a peculiar distribution in sperm head, being localized to nuclear matrix and acrosome and that sperm lacking nGPx4 are more prone to decondensation in vitro. In this
Boitani, Carla+8 more
core +1 more source
DISEASE DIVERSITY AND HUMAN FERTILITY [PDF]
The existence of parasitic constraints on the evolution of life-history traits in free-living organisms has been demonstrated in several plant and animal species. However, the association between different diseases and human traits is virtually unknown.
Guégan, Jean-François+4 more
openaire +6 more sources
Single-cell analysis of [Ca2+]i signalling in sub-fertile men:characteristics and relation to fertilization outcome [PDF]
STUDY QUESTIONWhat are the characteristics of progesterone-induced (CatSper-mediated) single cell [Ca2+]i signals in spermatozoa from sub-fertile men and how do they relate to fertilizing ability?SUMMARY ANSWERSingle cell analysis of progesterone-induced
Barratt, Christopher L.R.+7 more
core +4 more sources
THE INFLUENCE OF RADIATION ON HUMAN FERTILITY [PDF]
The number of children born to 180 females exposed to abdominal fluoroscopy in connection with an attack of intussusception in infancy or childhood was compared to the number born to women who were treated for the same disease without fluoroscopy. No difference was found between the number of children born or the age distribution of birth between the ...
L. Mondorf, M. Faber
openaire +4 more sources