Results 131 to 140 of about 9,011,517 (357)

Mitochondrial Replacement Techniques and Mexico’s Rule of Law: On the Legality of the First Maternal Spindle Transfer Case [PDF]

open access: yes, 2017
News about the first baby born after a mitochondrial replacement technique (MRT; specifically maternal spindle transfer) broke on September 27, 2016 and, in a matter of hours, went global.
Palacios-González, César
core  

Diagnosis of abnormal human fertilization status based on pronuclear origin and/or centrosome number

open access: yesJournal of Assisted Reproduction and Genetics, 2015
Y. Kai, K. Iwata, Y. Iba, Y. Mio
semanticscholar   +1 more source

Endometrial Assembloid Model Reveals Endometrial Gland Development Regulation by Estradiol‐Driven WNT7B Suppression

open access: yesAdvanced Science, EarlyView.
This study developed a 3D endometrial assembloid model to study how uterine glands form and develop. They discovered key interactions between different cell types and identified WNT7B as a regulator controlled by estradiol‐mediated TGFβ1‐VDR interaction.
Xintong Li   +12 more
wiley   +1 more source

Oocyte cryopreservation and in vitro culture affect calcium signalling during human fertilization.

open access: yesHuman Reproduction, 2014
D. Nikiforaki   +8 more
semanticscholar   +1 more source

5‐Hydroxymethylcytosine Dynamics Reveals Coordinated Reprogramming of Parental Genomes and X Chromosome Dosage Balance in Mouse SCNT Embryos

open access: yesAdvanced Science, EarlyView.
Genome‐wide, high‐resolution profiling of hydroxymethylation in mouse SCNT embryos reveals a transient, allele‐symmetric 5hmC reprogramming pattern distinct from natural embryos, with X‐chromosomes and imprinting control regions resistant to proper remodeling.
Zeming Xiang   +9 more
wiley   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

Age-associated aberrations of the cumulus-oocyte interaction and in the zona pellucida structure reduce fertility in female mice

open access: yesCommunications Biology
, One of the major age-related declines in female reproductive function is the reduced quantity and quality of oocytes. Here we demonstrate that structural changes in the zona pellucida (ZP) were associated with decreased fertilization rates from 34- to ...
Yu Ishikawa-Yamauchi   +11 more
doaj   +1 more source

Human fertilization: epididymal hCRISP1 mediates sperm-zona pellucida binding through its interaction with ZP3.

open access: yesMolecular human reproduction, 2014
J. Maldera   +10 more
semanticscholar   +1 more source

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