Results 171 to 180 of about 9,011,517 (357)
Single-cell sequencing shows mosaic aneuploidy in most human embryos
The Journal of Clinical InvestigationMammalian preimplantation embryos often contain chromosomal defects that arose in the first divisions after fertilization and affect a subpopulation of cells — an event known as mosaic aneuploidy. In this issue of the JCI, Chavli et al.
Sarah A. Robertson, Robert I. Richards
doaj +1 more source
Concentrations of stromal cell-derived factor-1 in human follicular fluids are associated with clinical in vitro fertilization outcomes [PDF]
, 2019 Hidetaka Okada, Akemi Nishigaki
openalex +1 more source
Advanced Science, EarlyView.Perfluorooctane sulfonate (PFOS) exposure disrupts oocyte maturation and early embryonic development. This study elucidates the mechanism by which enhanced O‐GlcNAcylation of FOXK1 underlies the PFOS‐induced reduction of progesterone levels in granulosa cells and the disturbance of follicular microenvironment.
Shuwen Han +16 more
wiley +1 more source
Advanced Science, EarlyView.This study highlights the significance of non‐canonical splicing variants in male infertility, a factor often overlooked during the analysis of high‐throughput sequencing data. Incorporating the non‐canonical splicing variants prioritization in the genetic analysis pipeline will increase the genetic diagnosis of patients with male infertility ...
Kuokuo Li +22 more
wiley +1 more source
Zona‐free hamster eggs: Their use in assessing fertilizing capacity and examining chromosomes of human spermatozoa [PDF]
, 1984 Ryuzo Yanagimachi
openalex +1 more source
The Microbiota Shapes Central Nervous System Myelination in Early Life
Advanced Science, EarlyView.Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch +13 more
wiley +1 more source
O-102. In-vitro fertilization: poor ovarian response to human gonadotrophins in overweight patients and in women over 35 years of age [PDF]
, 1999 L. Perotti +6 more
openalex +1 more source
ERp57 is a potential biomarker for human fertilization capability.
Molecular human reproduction, 2007 Jingjing Zhang +9 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study identifies ESM1 as an endogenous anticoagulant that modulates venous thrombosis. It shows that ESM1 deficiency triggers vascular occlusion in zebrafish and mice, whereas its restoration or overexpression prolongs clot‐formation time. Mechanistic analyses reveal that ESM1 activates HCII through its dermatan‐sulfate chain, uncovering a ...
Changsheng Chen +10 more
wiley +1 more source
Microbial Contributions to Primate Reproduction. [PDF]
Evol AnthropolCarboni S, Asangba AE, Melin AD.
europepmc +1 more source