Results 161 to 170 of about 10,288,978 (312)

Human genetics of Whipple's disease. [PDF]

Curr Opin Rheumatol
Rosain J, Casanova JL, Bustamante J.
europepmc   +1 more source

Combined effects of host genetics and diet on human gut microbiota and incident disease in a single population cohort

Nature Genetics, 2020
Y. Qin, A. Havulinna, Y. Liu, P. Jousilahti, S. Ritchie, A. Tokolyi, J. Sanders, L. Valsta, M. Brozynska, Q. Zhu, A. Tripathi, Y. Vázquez-Baeza, R. Loomba, S. Cheng, M. Jain, T. Niiranen, L. Lahti, R. Knight, V. Salomaa, M. Inouye, G. Méric   +20 more
semanticscholar   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

New horizons of human genetics in digestive diseases. [PDF]

eGastroenterology, 2023
Chen L, Lv G.
europepmc   +1 more source

Human Genetics of Addiction: New Insights and Future Directions

Current Psychiatry Reports, 2018
D. Hancock, Christina A Markunas, L. Bierut, Eric O. Johnson   +3 more
semanticscholar   +1 more source

A Human in Human Genetics [PDF]

Cell, 2019
openaire   +2 more sources

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Using human genetics to understand the epidemiological association between child obesity at different ages and MASLD. [PDF]

Int J Surg
Ge Q, Zhang L, Cai J, Sun Z, Yu C, Liu Z, Xiao C.   +6 more
europepmc   +1 more source

Measuring intolerance to mutation in human genetics

Nature Genetics, 2018
Z. Fuller, Jeremy J. Berg, H. Mostafavi, Guy Sella, M. Przeworski   +4 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source