Results 171 to 180 of about 1,575,758 (358)

Digest of Russian Space Life Sciences, issue 33 [PDF]

open access: yes
This is the thirty-third issue of NASA's USSR Space Life Sciences Digest. It contains abstracts of 55 papers published in Russian journals. The abstracts in this issue have been identified as relevant to the following areas of space biology and medicine:
Rowe, Joseph   +2 more
core   +1 more source

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

open access: yesMolecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop   +10 more
wiley   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Human Genetics [PDF]

open access: yesJournal of Medical Genetics, 1964
openaire   +1 more source

Identifying creative research accomplishments : methodology and results for nanotechnology and human genetics [PDF]

open access: yes
Motivated by concerns about the organizational and institutional conditions that foster research creativity in science, we focus on how creative research can be defined, operationalized, and empirically identified.
Heinze, Thomas   +3 more
core  

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

open access: yesMolecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski   +19 more
wiley   +1 more source

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