Results 241 to 250 of about 1,645,811 (308)

Genetics of Human Growth

, 2006
Tsutomu Ogata
openalex   +2 more sources

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Role of HLA-G and other immune mechanisms in pregnancy

Open Life Sciences, 2013
Durmanova Vladimira, Homolova Monika, Drobny Juraj, Shawkatova Ivana, Buc Milan   +4 more
doaj   +1 more source

Prenatal diagnosis following preimplantation genetic testing (PGT): recommendations of the Italian Society of Human Genetics (SIGU). [PDF]

J Assist Reprod Genet
Grati FR, Capalbo A, Gabbiato I, Battaglia P, Pittalis MC, Bizzoco D, Cardarelli L, Gatta V, Lonardo F, Novelli A, Bernardini L, Zuccarello D, Italian Society of Human Genetics (SIGU).   +12 more
europepmc   +1 more source

Genomic landscape in the human vaginal microbiome links to host phenotypes and genetics

陈晨(Chen Chen)
openalex   +1 more source

Introduction to mammalian genome special issue: the combined role of genetics and environment relevant to human disease outcomes

, 2018
Ivan Rusyn, Steven R. Kleeberger, Kimberly A. McAllister, John E. French, Karen L. Svenson   +4 more
openalex   +2 more sources

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Comparing genomic studies in animal breeding and human genetics: focus on disease-related traits in livestock - A review. [PDF]

Anim Biosci
Gervais O, Nagamine Y.
europepmc   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source