Results 61 to 70 of about 10,086,238 (407)

Thousands of Qatari genomes inform human migration history and improve imputation of Arab haplotypes

open access: yesNature Communications, 2021
Arab populations are relatively understudied, especially their genetic architecture and historical relationship with early founders of the ancient Near East.
Rozaimi Mohamad Razali   +10 more
doaj   +1 more source

Direct-to-consumer genetic testing: where and how does genetic counseling fit? [PDF]

open access: yes, 2017
Direct-to-consumer genetic testing for disease ranges from well-validated diagnostic and predictive tests to ‘research’ results conferring increased risks.
Anna Middleton   +8 more
core   +1 more source

Recontacting patients in clinical genetics services: recommendations of the European Society of Human Genetics

open access: yesEuropean Journal of Human Genetics, 2018
Technological advances have increased the availability of genomic data in research and the clinic. If, over time, interpretation of the significance of the data changes, or new information becomes available, the question arises as to whether recontacting
D. Carrieri   +19 more
semanticscholar   +1 more source

The genetics of human obesity [PDF]

open access: yesAnnals of the New York Academy of Sciences, 2013
It has long been known that there is a genetic component to obesity, and that characterizing this underlying factor would likely offer the possibility of better intervention in the future. Monogenic obesity has proved to be relatively straightforward, with a combination of linkage analysis and mouse models facilitating the identification of multiple ...
Struan F.A. Grant   +2 more
openaire   +3 more sources

Conflation of Short Identity-by-Descent Segments Bias Their Inferred Length Distribution

open access: yesG3: Genes, Genomes, Genetics, 2016
Identity-by-descent (IBD) is a fundamental concept in genetics with many applications. In a common definition, two haplotypes are said to share an IBD segment if that segment is inherited from a recent shared common ancestor without intervening ...
Charleston W. K. Chiang   +2 more
doaj   +1 more source

Behavioural Genetics in Criminal Cases: Past, Present and Future [PDF]

open access: yes, 2006
Researchers studying human behavioral genetics have made significant scientific progress in enhancing our understanding of the relative contributions of genetics and the environment in observed variations in human behavior. Quickly outpacing the advances
Bernet, William, Farahany, Nita A.
core   +1 more source

Evolution of Genetic Techniques: Past, Present, and Beyond. [PDF]

open access: yes, 2015
Genetics is the study of heredity, which means the study of genes and factors related to all aspects of genes. The scientific history of genetics began with the works of Gregor Mendel in the mid-19th century.
Cogulu, O.   +5 more
core   +4 more sources

Human Genetics and Drug Development.

open access: yesNew England Journal of Medicine, 2019
Current tools in the field of human genetics can reliably estimate both the intended and the adverse effects of modifying a therapeutic target to guide the clinical development of medicines.1 The d...
M. Holmes
semanticscholar   +1 more source

Infection Models for Pine Wilt Disease on the Basis of Vector Behaviors

open access: yesPopulation Ecology, EarlyView.
Infection models for pine wilt disease without vector density were built to estimate the transmission coefficient of the pathogenic nematode. The models successfully simulated the annual change in the density of infected trees for four pine stands. ABSTRACT Pine wilt disease is caused by the pinewood nematode (Bursaphelenchus xylophilus Steiner et ...
Katsumi Togashi
wiley   +1 more source

Protease inhibitor (Pi) locus, fertility and twinning [PDF]

open access: yes, 1992
In a sample of 160 Dutch twin pairs and their parents, we found that mothers of dizygotic twins had frequencies of the S and Z alleles at the protease inhibitor (Pi) locus that were 3 times higher than a control sample.
Bank, R.A.   +3 more
core   +1 more source

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