Results 91 to 100 of about 988,007 (335)

Long antisense non-coding RNAs and the epigenetic regulation of gene expression

open access: yesBiomolecular Concepts, 2013
Shortly after the completion of the human genome project in 2003, the Encode project was launched. The project was set out to identify the functional elements in the human genome, and unexpectedly it was found that >80% of the genome is transcribed.
Vadaie Nadia, Morris Kevin V.
doaj   +1 more source

Open questions: How many genes do we have?

open access: yesBMC Biology, 2018
Seventeen years after the initial publication of the human genome, we still haven’t found all of our genes. The answer turns out to be more complex than anyone had imagined when the Human Genome Project began.
Steven L. Salzberg
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Yeast: one cell, one reference sequence, many genomes?

open access: yesNew Genetics and Society, 2019
The genome of Saccharomyces cerevisiae – brewer’s or baker’s yeast – was the first eukaryotic genome to be sequenced in 1996. The identity of that yeast genome has been not just a product of sequencing, but also of its use after sequencing and ...
Erika Szymanski   +2 more
doaj   +1 more source

Human Genome Project

open access: yes, 1998
Abstract : The study reviews Department of Energy supported aspects of the United States Human Genome Project, the joint National Institutes of Health/Department of Energy program to characterize all human genetic material, to discover the set of human genes, and to render them accessible for further biological study.
S. Block   +12 more
openaire   +3 more sources

Iranian human genome project: Overview of a research process among Iranian ethnicities

open access: yesIndian Journal of Human Genetics, 2009
The Human Genome Project (HGP) refers to the international scientific research program, formally begun in October 1990 and completed in 2003, mainly designated to discover all the human genes, analyzing the structure of human DNA and determining the ...
K. Banihashemi
semanticscholar   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

Big data, open science and the brain: lessons learned from genomics

open access: yesFrontiers in Human Neuroscience, 2014
The BRAIN Initiative aims to break new ground in the scale and speed of data collection in neuroscience, requiring tools to handle data in the magnitude of yottabytes (1024).
Suparna eChoudhury   +3 more
doaj   +1 more source

Human Genome Project

open access: yesJournal of the Korean Medical Association, 1997
The study reviews Department of Energy supported aspects of the United States Human Genome Project, the joint National Institutes of Health/Department of Energy program to characterize all human genetic material, to discover the set of human genes, and to render them accessible for further biological study.
openaire   +2 more sources

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