Results 91 to 100 of about 948,823 (313)
Long antisense non-coding RNAs and the epigenetic regulation of gene expression
Biomolecular Concepts, 2013 Shortly after the completion of the human genome project in 2003, the Encode project was launched. The project was set out to identify the functional elements in the human genome, and unexpectedly it was found that >80% of the genome is transcribed.
Vadaie Nadia, Morris Kevin V.
doaj +1 more source
History, philosophy, and science education: reflections on genetics 20 years after the human genome project. [PDF]
Hist Philos Life Sci, 2023 Meunier R.
europepmc +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
Molecular Oncology, EarlyView.This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu +15 more
wiley +1 more source
Yeast: one cell, one reference sequence, many genomes?
New Genetics and Society, 2019 The genome of Saccharomyces cerevisiae – brewer’s or baker’s yeast – was the first eukaryotic genome to be sequenced in 1996. The identity of that yeast genome has been not just a product of sequencing, but also of its use after sequencing and ...
Erika Szymanski +2 more
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Big data, open science and the brain: lessons learned from genomics
Frontiers in Human Neuroscience, 2014 The BRAIN Initiative aims to break new ground in the scale and speed of data collection in neuroscience, requiring tools to handle data in the magnitude of yottabytes (1024).
Suparna eChoudhury +3 more
doaj +1 more source
Iranian human genome project: Overview of a research process among Iranian ethnicities
Indian Journal of Human Genetics, 2009 The Human Genome Project (HGP) refers to the international scientific research program, formally begun in October 1990 and completed in 2003, mainly designated to discover all the human genes, analyzing the structure of human DNA and determining the ...
K. Banihashemi
semanticscholar +1 more source
Molecular Oncology, EarlyView.TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair +17 more
wiley +1 more source
Journal of the Korean Medical Association, 1997 The study reviews Department of Energy supported aspects of the United States Human Genome Project, the joint National Institutes of Health/Department of Energy program to characterize all human genetic material, to discover the set of human genes, and to render them accessible for further biological study.
openaire +2 more sources
Molecular Oncology, EarlyView.There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes +20 more
wiley +1 more source
, 1998 Abstract : The study reviews Department of Energy supported aspects of the United States Human Genome Project, the joint National Institutes of Health/Department of Energy program to characterize all human genetic material, to discover the set of human genes, and to render them accessible for further biological study.
S. Block +12 more
openaire +3 more sources