Results 151 to 160 of about 988,007 (335)

The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh, Ruchi Tanavade, Nik Krajnc, Fabian Föttinger, Theresa König, Martin Krenn, Lukas Haider, Barbara Kornek, Fritz Leutmezer, Kerstin U. Ludwig, Stefan Macher, Tobias Monschein, Markus Ponleitner, Paulus Rommer, Christiane Schmied, Karin Zebenholzer, Tobias Zrzavy, Gudrun Zulehner, Franziska Di Pauli, Axel Schmidt, Harald Hegen, Berthold Pemp, Thomas Berger   +22 more
wiley   +1 more source

The Human Genome Project: What's in it for the Pediatric Gastroenterologist?

, 2000
W. Allan Walker
openalex   +1 more source

Single‐Cell RNA Seq in Sydenham Chorea Shows B Cell HLA‐DR/DQ Upregulation and Plasma Cell Proteasomal Activation

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The pathogenesis of Sydenham chorea remains unclear. We report a 10‐year‐old girl presenting with subacute chorea and mild carditis following Streptococcal throat infection. Single‐cell RNA sequencing on 30,794 peripheral immune cells from the patient and two sex‐matched controls revealed nine immune cell clusters.
Velda X. Han, Brooke A. Keating, Brian S. Gloss, Xianzhong Lau, Ruwani Dissanayake, Hiroya Nishida, Jessica Hayes, Shrujna Patel, Shekeeb S. Mohammad, Russell C. Dale   +9 more
wiley   +1 more source

Lessons from the Human Genome Project: Modesty, Honesty, and Realism. [PDF]

Front Genet, 2017
Emmert-Streib F, Dehmer M, Yli-Harja O.
europepmc   +1 more source

Commercial molecular diagnostics in the U.S.: The Human Genome Project to the clinical laboratory [PDF]

, 2002
Jean Amos, Meeta Patnaik
openalex   +1 more source

Exploring Nasal Structural‐Microbial Interactions in Multiple Sclerosis‐Associated Olfactory Impairment

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Olfactory dysfunction is frequently observed in patients with multiple sclerosis (MS); however, its underlying mechanisms remain poorly understood. To date, no studies have directly examined the nasal mucosal microbiota in MS. This study aimed to explore potential relationships among olfactory function, nasal microbiota composition,
Zidan Gao, Zhuoma Danzhen, Yao Li, Junyu Zhu, Lan Chu, Zhang Yang   +5 more
wiley   +1 more source

Human Genome Project and Parasitic Infections

European Journal of Inflammation, 2004
S. Frydas, E. Karagouni, T. Iezzi, D. Kempuraj, C.M.V. Conti, W. Boucher, N. G. Papadoopoulou, J. Donelan, B. Madhappan, R. Letourneau, G. Carratelli, A. Grilli, F. Conti, G. Riccioni, D. Tripodi, F. Meneghini, L. Stellin, G. Sabatino   +17 more
doaj   +1 more source

The impact of the human genome project on complex disease. [PDF]

Genes (Basel), 2014
Bailey JN, Pericak-Vance MA, Haines JL.
europepmc   +1 more source

Waiting for the working draft from the human genome project

, 2000
Lon R. Cardon
openalex   +2 more sources

The Human Genome Project as a Singular Episode in the History of Genomics [PDF]

, 2022
Miguel García-Sancho, Rhodri Leng, Gil Viry, Mark Wong, Niki Vermeulen, James Lowe   +5 more
openalex   +1 more source