Results 71 to 80 of about 923,221 (312)

“Negativibacillus massiliensis” gen. nov., sp. nov., isolated from human left colon

open access: yesNew Microbes and New Infections, 2017
We report here the main characteristics of “Negativibacillus massiliensis” strain Marseille-P3213T, isolated from a human left-colon wash sample.
D. Ricaboni   +5 more
doaj   +1 more source

Relating the metatranscriptome and metagenome of the human gut [PDF]

open access: yes, 2014
Although the composition of the human microbiome is now wellstudied, the microbiota’s \u3e8 million genes and their regulation remain largely uncharacterized.
Boylan, Matthew R.   +13 more
core   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Chocolate, gut microbiota, and human health [PDF]

open access: yesFrontiers in Pharmacology, 2013
With the advances in molecular biology techniques, the association between changes in the gut microbiota and human diseases or disorders is becoming more evident. These health issues include aging (Rehman, 2012), oxidative stress (Qiao et al., 2012), blood pressure and atherosclerosis (Queipo-Ortuno, 2012), diabetes (Wen et al., 2008; Larsen et al ...
openaire   +3 more sources

“Ihubacter massiliensis”: a new bacterium isolated from the human gut

open access: yesNew Microbes and New Infections, 2016
We report here the main characteristics of “Ihubacter massiliensis,” strain Marseille-P2843T (CSUR P2843), a new genus of the Clostridiales family isolated from a stool sample from a healthy 29-year-old woman.
S. Ndongo   +4 more
doaj   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Links between gut microbiome composition and fatty liver disease in a large population sample

open access: yesGut Microbes, 2021
Fatty liver disease is the most common liver disease in the world. Its connection with the gut microbiome has been known for at least 80 y, but this association remains mostly unstudied in the general population because of underdiagnosis and small sample
Matti O. Ruuskanen   +16 more
doaj   +1 more source

Synthetic gut microbiome: Advances and challenges

open access: yesComputational and Structural Biotechnology Journal, 2021
An exponential rise in studies regarding the association among human gut microbial communities, human health, and diseases is currently attracting the attention of researchers to focus on human gut microbiome research. However, even with the ever-growing
Humphrey A. Mabwi   +7 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

Human gut Bacteroides capture vitamin B12 via cell surface-exposed lipoproteins. [PDF]

open access: yes, 2018
Human gut Bacteroides use surface-exposed lipoproteins to bind and metabolize complex polysaccharides. Although vitamins and other nutrients are also essential for commensal fitness, much less is known about how commensal bacteria compete with each other
Barry, Natasha A   +5 more
core  

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