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Understanding dysbiosis and resilience in the human gut microbiome: biomarkers, interventions, and challenges [PDF]

open access: yesFrontiers in Microbiology
The healthy gut microbiome is important in maintaining health and preventing various chronic and metabolic diseases through interactions with the host via different gut–organ axes, such as the gut-brain, gut-liver, gut-immune, and gut-lung axes.
Azadeh Safarchi   +5 more
doaj   +2 more sources

Synthetic gut microbiome: Advances and challenges

open access: yesComputational and Structural Biotechnology Journal, 2021
An exponential rise in studies regarding the association among human gut microbial communities, human health, and diseases is currently attracting the attention of researchers to focus on human gut microbiome research. However, even with the ever-growing
Humphrey A. Mabwi   +7 more
doaj   +1 more source

Westlake Gut Project: A consortium of microbiome epidemiology for the gut microbiome and health research in China

open access: yesMedicine in Microecology, 2022
Microbiome epidemiology is an emerging field for the discovery of novel disease biomarkers or intervention targets in human epidemiological studies. The determinants and consequences of human microbiome variations, especially for the gut microbiome, are ...
Wanglong Gou   +19 more
doaj   +1 more source

Genetic analysis of seed traits in Sorghum bicolor that affect the human gut microbiome

open access: yesNature Communications, 2022
Diet affects the human gut microbiome, but studies linking crop genetics to seed traits that influence the human gut microbiome are lacking. Here, the authors develop an in vitro microbiome screening method and reveal the association between sorghum ...
Qinnan Yang   +7 more
doaj   +1 more source

Research progress of gut microbiome in autoimmune diseases of nervous system

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2022
Gut microbiome is the most direct external environment of human body, which plays a vital role in maintaining human health. Gut microbiome maintains the homeostasis of the human immune system, which can coexist with the host and affect the nutrition ...
TANG Shi, FENG Jin⁃zhou, QIN Xin⁃yue
doaj   +1 more source

Gut Microbiome Toxicity: Connecting the Environment and Gut Microbiome-Associated Diseases

open access: yesToxics, 2020
The human gut microbiome can be easily disturbed upon exposure to a range of toxic environmental agents. Environmentally induced perturbation in the gut microbiome is strongly associated with human disease risk. Functional gut microbiome alterations that
Pengcheng Tu   +8 more
doaj   +1 more source

Comprehensive Assessment of Functional Effects of Commonly Used Sugar Substitute Sweeteners on Ex Vivo Human Gut Microbiome

open access: yesMicrobiology Spectrum, 2022
The composition and function of the human gut microbiome are often associated with health and disease status. Sugar substitute sweeteners are widely used food additives, although many studies using animal models have linked sweetener consumption to gut ...
Zhongzhi Sun   +8 more
doaj   +1 more source

Material Engineering in Gut Microbiome and Human Health

open access: yesResearch, 2022
Tremendous progress has been made in the past decade regarding our understanding of the gut microbiome’s role in human health. Currently, however, a comprehensive and focused review marrying the two distinct fields of gut microbiome and material research
Letao Yang   +5 more
doaj   +1 more source

Gut microbiome dysbiosis in men who have sex with men increases HIV infection risk through immunity homeostasis alteration

open access: yesFrontiers in Cellular and Infection Microbiology, 2023
ObjectivesRecent studies pointed out that gut microbiome dysbiosis in HIV infection was possibly confounded in men who have sex with men (MSM), but there is a lack of evidence. It also remained unclear how MSM-associated gut microbiome dysbiosis affected
Kangjie Li   +5 more
doaj   +1 more source

Biomimetic Gut Model Systems for Development of Targeted Microbial Solutions for Enhancing Warfighter Health and Performance

open access: yesmSystems, 2020
The human gut microbiome plays a vital role in both health and disease states and as a mediator of cognitive and physical performance. Despite major advances in our understanding of the role of gut microbes in host physiology, mechanisms underlying human-
Lauren M. Brinkac   +3 more
doaj   +1 more source

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