Results 171 to 180 of about 121,767 (265)

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

open access: yesFood Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao   +8 more
wiley   +1 more source

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

open access: yesFood Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu   +8 more
wiley   +1 more source

Metaproteomic Analysis to Assess the Impact of Storage Media on Human Gut Microbiome in Fecal Samples. [PDF]

open access: yesProteomics
Duong VA   +6 more
europepmc   +1 more source

Influence of Nanomaterials and Nanocomposites on the Nutrient Composition

open access: yesFood Safety and Health, EarlyView.
Nanomaterials and nanocomposites enhance crop nutrition and food quality by improving nutrient availability, plant uptake, and bioavailability through controlled delivery and nano‐encapsulation. Their applications in agriculture and food systems enable sustainable biofortification, improved preservation, and functional foods, while emphasizing safety ...
Akanksha Dwivedi   +4 more
wiley   +1 more source

<i>Flavonifractor plautii</i> as a Next-Generation Probiotic Enhancing the NGP F/P Index in a Simulated Human Gut Microbiome Ecosystem. [PDF]

open access: yesPharmaceutics
Shuvo MSH   +16 more
europepmc   +1 more source

Interkingdom Interactions in the Gut: Ecological Mechanisms, Homeostasis, and Therapeutic Modulation

open access: yesGut Medicine, EarlyView.
ABSTRACT The gut microbiota constitutes a highly complex and dynamic ecosystem that profoundly influences host physiology, metabolism, and immunity. This review provides an integrative overview of the mechanisms through which gut microorganisms—particularly bacteria and fungi—interact with host cells and with each other to maintain intestinal ...
Rui‐Qi Wei   +5 more
wiley   +1 more source

Toward a Typology of Patients With Head and Neck Cancer: Biopsychosocial Profiles Predicting Longitudinal Quality of Life

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Quality of life (QoL) in head and neck cancer (HNC) is influenced by complex biopsychosocial factors, yet few longitudinal studies have examined these relationships immediately post‐treatment. Methods In this prospective study, 232 patients newly diagnosed with primary HNC completed psychometric assessments, clinical interviews, and
Haley Deamond   +18 more
wiley   +1 more source

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