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Diet, the human gut microbiota, and IBD
Anaerobe, 2013The human gut contains a vast number of microorganisms known collectively as the "gut microbiota". Despite its importance in maintaining the health of the host, growing evidence suggests the gut microbiota may also be an important factor in the pathogenesis of various diseases, a number of which have shown a rapid increase in incidence over the past ...
Gary D Wu, James D Lewis
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Diversity, stability and resilience of the human gut microbiota [PDF]
Nature, 2012 Trillions of microbes inhabit the human intestine, forming a complex ecological community that influences normal physiology and susceptibility to disease through its collective metabolic activities and host interactions. Understanding the factors that underlie changes in the composition and function of the gut microbiota will aid in the design of ...
Jeffrey I. Gordon +2 more
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Synthetic ecology of the human gut microbiota
Nature Reviews Microbiology, 2019Despite recent advances in sequencing and culturing, a deep knowledge of the wiring and functioning of the human gut ecosystem and its microbiota as a community is still missing. A holistic mechanistic understanding will require study of the gut microbiota as an interactive and spatially organized biological system, which is difficult to do in complex ...
Gino Vrancken +4 more
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The Gut Microbiota and Obesity in Humans
2016In recent years, the human gut microbiome has been linked to a wide range of host metabolic effects, via modulation of energy harvesting, lipid and glucose metabolism, inflammatory responses, and brain-gut axis activity. Numerous observational studies have yielded important results regarding the structure and adaptive responses of the gut microbiota in
Efthymakis K. +3 more
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Implication of Gut Microbiota in Human Health
CNS & Neurological Disorders - Drug Targets, 2014Gut-microbiota (GM) is considered a hidden metabolic organ of the human body, providing biochemical pathways which are absent in the host. Balanced diet with calorie restriction (CR) promotes growth of healthy microbiota, leading to longevity by down-regulating inflammatory responses.
Imran, Khan +6 more
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Human gut microbiota and Parkinson's disease
2022The bidirectional communication between the gut and the brain has come up very fascinating in recent years. Many studies have reported that the onset of gastrointestinal issues appears long before the actual manifestation of Parkinson's disease (PD) symptoms. Disturbances in the gut-brain axis have been found to be linked with PD.
Archana, Pant +3 more
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The gut microbiota: A treasure for human health
Biotechnology Advances, 2016The interplay between the host and host-associated gut microbiota is an area of increasing interest during the recent decade. From young infants to elderly people, from primitive tribes to modern societies, accumulating evidence has suggested the association of critical physiological roles of gut microbiota in the pathogenesis of a variety of human ...
Daotong, Li +4 more
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Proteomics, human gut microbiota and probiotics
Expert Review of Proteomics, 2011The various bacterial communities associated with humans have many functions and the gut microbiota has a major role in the host. Bacterial imbalance in the gut, known as dysbiosis, has therefore been linked to several diseases. Probiotics, that is, microbial strains that have beneficial effects on the host, are thought to benefit this intestinal ...
Julio, Aires, Marie-José, Butel
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Human Gut Microbiota in Cardiovascular Disease
Comprehensive PhysiologyAbstract The gut ecosystem, termed microbiota, is composed of bacteria, archaea, viruses, protozoa, and fungi and is estimated to outnumber human cells. Microbiota can affect the host by multiple mechanisms, including the synthesis of metabolites and toxins, modulating inflammation and interaction with other ...
Daniel, Ronen +6 more
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A Nutritional Anthropology of the Human Gut Microbiota
2015The feeding strategy of Homo sapiens appears to be characterized by an extraordinary omnivorism, which has no equal among mammals with the exception to some extent of the Suidae and the brown bear. This strategy allows him to have a diet that is able to capture all substances and nutrients necessary for its energy and structural needs, according to the
De Filippo, Carlotta +1 more
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