Results 91 to 100 of about 78,351 (172)

The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset

Advanced Science, Volume 12, Issue 45, December 4, 2025.
The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng, Hua Wang, Li Zhang, Shiping Li, Yuan Yuan, Mengting Tian, Yi Qu, Junjie Ying, Meicen Zhou, Yong Hu, Jinglan Huang, Rong Zou, Fengyan Zhao, Xiaojuan Su, Qian Liu, Yan He, Jinxing Feng, Weimin Huang, Ying Luo, Zhemin Zhou, Wei Shen, Dezhi Mu, Shaopu Wang   +22 more
wiley   +1 more source

Efficient Recovery of Complete Gut Viral Genomes by Combined Short‐ and Long‐Read Sequencing

Advanced Science
Current metagenome assembled human gut phage catalogs contained mostly fragmented genomes. Here, comprehensive gut virome detection procedure is developed involving virus‐like particle (VLP) enrichment from ≈500 g feces and combined sequencing of short ...
Jingchao Chen, Chuqing Sun, Yanqi Dong, Menglu Jin, Senying Lai, Longhao Jia, Xueyang Zhao, Huarui Wang, Na L. Gao, Peer Bork, Zhi Liu, Wei‐Hua Chen, Xing‐Ming Zhao   +12 more
doaj   +1 more source

Advances in the Gut‐Lung Axis and Bronchial Asthma: From Mechanisms to Therapeutic Potential

Clinical and Translational Allergy, Volume 15, Issue 12, December 2025.
ABSTRACT Background Bronchial asthma (hereafter referred to as asthma) is a heterogeneous disease characterized by chronic airway inflammation, airway hyperresponsiveness (AHR), and reversible airflow limitation. Recent advancements in the “gut‐lung” axis concept have elucidated the intricate immunometabolic crosstalk between the gastrointestinal tract
Ting Zheng, Yi Huang, Hongmei Yao
wiley   +1 more source

Structural changes in the gut virome of patients with atherosclerotic cardiovascular disease

Microbiology Spectrum
The gut microbiota is an important risk factor and therapeutic target in atherosclerotic cardiovascular disease (ACVD), a leading cause of morbidity and mortality worldwide.
Youshan Li, Jie Ma, Jinxin Meng, Shenghui Li, Yan Zhang, Wei You, Xulin Sai, Jianfeng Yang, Shuo Zhang, Wen Sun   +9 more
doaj   +1 more source

The Chinese gut virus catalogue reveals gut virome diversity and disease-related viral signatures

Genome Medicine
Background The gut viral community has been increasingly recognized for its role in human physiology and health; however, our understanding of its genetic makeup, functional potential, and disease associations remains incomplete.
Qiulong Yan, Liansha Huang, Shenghui Li, Yue Zhang, Ruochun Guo, Pan Zhang, Zhixin Lei, Qingbo Lv, Fang Chen, Zhiming Li, Jinxin Meng, Jing Li, Guangyang Wang, Changming Chen, Hayan Ullah, Lin Cheng, Shao Fan, Wei You, Yan Zhang, Jie Ma, Shanshan Sha, Wen Sun   +21 more
doaj   +1 more source

Gut Bacteriophage: Current Understanding and Challenges

Frontiers in Endocrinology, 2019
The gut microbiome is widely accepted to have a significant impact on human health yet, despite years of research on this complex ecosystem, the contributions of different forces driving microbial population structure remain to be fully elucidated.
Thomas D. S. Sutton, Colin Hill
doaj   +1 more source

Possible Crosstalk and Alterations in Gut Bacteriome and Virome in HIV-1 Infection and the Associated Comorbidities Related to Metabolic Disorder

Viruses
Improved antiretroviral therapy (ART) has significantly increased the life expectancy of people living with HIV (PLWH). At the same time, other complications like metabolic syndrome (MetS) are coming up as new challenges to handle.
Komal Shrivastav, Hesham Nasser, Terumasa Ikeda, Vijay Nema   +3 more
doaj   +1 more source

Altered Phage‐Related Gene Profiles in Asthmatic Airways

Allergy, Volume 81, Issue 1, Page 252-255, January 2026.
Min‐Gyung Baek, Sangcheol Park, Young‐Chan Kim, Kyoung‐Hee Sohn, Jung Wook Kim, Kwang Jun Lee, Sang‐Heon Cho, Hye‐Ryun Kang, Hana Yi   +8 more
wiley   +1 more source

Viral communities of the human gut: metagenomic analysis of composition and dynamics

Mobile DNA, 2017
Background The numerically most abundant biological entities on Earth are viruses. Vast populations prey on the cellular microbiota in all habitats, including the human gut.
Varun Aggarwala, Guanxiang Liang, Frederic D. Bushman   +2 more
doaj   +1 more source

Gut virus axis: Unravelling viral contribution to gut microbiota dysbiosis and translational medicine in inflammatory bowel disease

Medicine in Microecology
The gut microbiota and immune system are significantly influenced by the human gut-virus axis, which is mostly composed of bacteriophages and eukaryotic viruses.
Naziya Akhtar, Chirag Jain, Shikha Baghel Chauhan, Indu Singh   +3 more
doaj   +1 more source