Results 101 to 110 of about 78,351 (172)

Longitudinal analysis of the enteric virome in paediatric subjects from the Free State Province, South Africa, reveals early gut colonisation and temporal dynamics

Virus Research
The gut of healthy neonates is devoid of viruses at birth, but rapidly becomes colonised by normal viral commensals that aid in important physiological functions like metabolism but can, in some instances, result in gastrointestinal illnesses.
Milton Tshidiso Mogotsi, Ayodeji Emmanuel Ogunbayo, Phillip Armand Bester, Hester Gertruida O'Neill, Martin Munene Nyaga   +4 more
doaj   +1 more source

Improving gut virome comparisons using predicted phage host information

mSystems
The human gut virome is predominantly made up of bacteriophages (phages), viruses that infect bacteria. Metagenomic studies have revealed that phages in the gut are highly individual specific and dynamic.
Michael Shamash, Anshul Sinha, Corinne F. Maurice   +2 more
doaj   +1 more source

AcrDB update: Predicted 3D structures of anti‐CRISPRs in human gut viromes

Protein Science
AbstractAnti‐CRISPR (Acr) proteins play a key role in phage‐host interactions and hold great promise for advancing genome‐editing technologies. However, finding new Acrs has been challenging due to their low sequence similarity. Recent advances in protein structure prediction have opened new pathways for Acr discovery by using 3D structure similarity ...
Minal Khatri, N. R. Siva Shanmugam, Xinpeng Zhang, Revanth Sai Kumar Reddy Patel, Yanbin Yin   +4 more
openaire   +2 more sources

The human gut virome: the dark matter of the human gut universe

The gut is home to trillions of microbes, with bacteria and viruses being its most abundant members, forming a dynamic ecosystem that profoundly influences human health. While gut bacterial communities have been linked to various health conditions, the viral component, known as the virome, has remained largely unexplored.
openaire   +1 more source

Another piece of puzzle for the human microbiome: the gut virome under dietary modulation

Journal of Genetics and Genomics
The virome is the most abundant and highly variable microbial consortium in the gut. Because of difficulties in isolating and culturing gut viruses and the lack of reference genomes, the virome has remained a relatively elusive aspect of the human microbiome.
Fengxiang Zhao, Jinfeng Wang
openaire   +2 more sources

Lactococcus A phages predict ACLF while Enterococcus B phages predict bacterial infection in decompensated cirrhosis

JHEP Reports
Background & Aims: As portal hypertension progresses in cirrhosis, bacterial translocation across a compromised gut barrier leads to endotoxemia, systemic inflammation and immune dysfunction.
Lore Van Espen, Maximilian Joseph Brol, Lila Close, Robert Schierwagen, Wenyi Gu, Marisa I. Keller, Boglarka Balogh, Anthony Fullam, Lander De Coninck, Tomohiro Nakamura, Michael Kuhn, Peer Bork, Wim Laleman, Jasmohan S. Bajaj, Maria Papp, Bernd Schnabl, Jonel Trebicka, Jelle Matthijnssens   +17 more
doaj   +1 more source

Unveiling the gut virome in human health and diseases [PDF]

International Journal of Clinical Virology, 2018
openaire   +1 more source

The gut and circulating virome: emerging players in aging and longevity. [PDF]

Front Aging
Badillo-Pazmay GV, Fortunato C, Cianfruglia L, Novazzi F, Spezia PG, Rosa L, Limongi D, Prezioso C, D'Argenio V, Scudiero O, Bevilacqua L, Malavolta M, Russo P, Maggi F, Balietti M, Giacconi R.   +15 more
europepmc   +1 more source

Metatranscriptomics reveals the horse gut RNA virome and a viral sharing network with human and domestic animals. [PDF]

Front Vet Sci
Li C, Liu K, Wei N, Hu S, Li X, Li C.
europepmc   +1 more source

Dynamics of gut bacteriophage in diversity outbred mice studied over lifespan and during extreme caloric restriction. [PDF]

Microbiome
Merenstein C, Litichevskiy L, Thaiss C, Collman RG, Bushman FD.   +4 more
europepmc   +1 more source