Results 101 to 110 of about 9,764,220 (350)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Risk Analysis of Acute Or Chronic Exposure to Arsenic of the Inhabitants in a District of Buenos Aires, Argentina

open access: yesJournal of Sustainable Development of Energy, Water and Environment Systems, 2016
The arsenic occurrence in the water constitutes a serious world health concern due to its toxicity. Depending on the intensity and duration of exposure, this element can be acutely lethal or may have a wide range of health effects in humans and animals ...
Cristina Vázquez   +3 more
doaj   +1 more source

A Style-Based Generator Architecture for Generative Adversarial Networks

open access: yes, 2019
We propose an alternative generator architecture for generative adversarial networks, borrowing from style transfer literature. The new architecture leads to an automatically learned, unsupervised separation of high-level attributes (e.g., pose and ...
Aila, Timo, Karras, Tero, Laine, Samuli
core   +1 more source

A replication study confirmed the EDAR gene to be a major contributor to population differentiation regarding head hair thickness in Asia [PDF]

open access: yes, 2008
Hair morphology is a highly divergent phenotype among human populations. We recently reported that a nonsynonymous SNP in the ectodysplasin A receptor (EDAR 1540T/C) is associated with head hair fiber thickness in an ethnic group in Thailand (Thai-Mai ...
Fujimoto Akihiro   +8 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

The form of the hair follicle in the human scalp as an indicator of human relationships [PDF]

open access: yes, 1991
The form of the hair follicle has been examined in some human isolates. There is no relationship between follicular structure and hair form, that is, similar hair forms may be the end product of different follicular structures.
Barber, L, Plomley, B
core   +2 more sources

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

open access: yesFEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan   +6 more
wiley   +1 more source

Sustainable composite development: Novel use of human hair as fiber in concrete

open access: yesCase Studies in Construction Materials, 2020
In the present era, to recycle waste and to reduce environmental pollution is the main objectives of sustainable development. Many researchers are working on new techniques and thinking for innovation in the field of concrete technology by utilizing the ...
Naraindas Bheel   +5 more
doaj   +1 more source

Potential applications of biosurfactant extract obtained from corn steep liquor in hair formulations [PDF]

open access: yes, 2016
[Excerpt] Biosurfactants (BS) have great advantages as an eco-friendly alternative to synthetic surfactants used in hair formulations. Human hair contains fatty acids (palmitic, palmitoleic, oleic and stearic acid) that prevent hair dryness and avoid the
Cruz, J. M.   +4 more
core  

A Cutibacterium acnes antibiotic modulates human skin microbiota composition in hair follicles

open access: yesScience Translational Medicine, 2020
Cutimycin, a thiopeptide antibiotic produced by the skin commensal Cutibacterium acnes, reduces Staphylococcus colonization of human skin hair follicles. A microbiota that is only skin deep Interspecies interactions influence the composition of microbial
J. Claesen   +16 more
semanticscholar   +1 more source

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