Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective We aim to comprehensively analyze how regional tumor and edema characteristics are associated with clinical presentations and survival outcomes in a large cohort of glioblastoma patients. Methods Patients with IDH‐wildtype glioblastoma who received brain MRI from 2010 to 2023 were included.
Daniel J. Zhou +16 more
wiley +1 more source
Health technology assessment of Herpes Zoster (shingles) vaccination
Herpes zoster, which is commonly known as shingles, affects approximately one in three people who have had chickenpox. Shingles is typically recognised by a painful blistering rash on the torso.
Health Information and Quality Authority (HIQA)
core
Fatty Acid Profile, Mineral Composition and Heavy Metal Contamination in Brown Bear (Ursus arctos) Muscle: Implications for Human Health Risk Assessment. [PDF]
Biol Trace Elem ResHaščík P +3 more
europepmc +1 more source
Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig +9 more
wiley +1 more source
Toxic Substances in Plastics, Micro- and Nanoplastics: Utilizing ATSDR's Plastics-Related Toxicological Profile Tool and Mixtures Framework for Human Health Risk Assessment. [PDF]
ToxicsMuianga CV +7 more
europepmc +1 more source
Peripheral Neutrophil Activation and Extracellular Trap Formation in Amyotrophic Lateral Sclerosis
Annals of Clinical and Translational Neurology, EarlyView.Markers of neutrophil activation are increased in plasma during ALS, and markers of NET formation associate with ALS survival. ABSTRACT Objectives Peripheral neutrophil levels in amyotrophic lateral sclerosis (ALS) inversely correlate with survival, suggesting a role for neutrophils in disease progression.
Lillia A. Baird +9 more
wiley +1 more source
Protocol for a health technology assessment of extending BowelScreen to those aged 50 to 54 years
Following a request from the National Screening Advisory Committee (NSAC), HIQA has commenced work on a health technology assessment (HTA) of extending Ireland’s national colorectal cancer screening programme, BowelScreen, to those aged 50 to 54 years ...
Health Information and Quality Authority (HIQA)
core
Advancing human health risk assessment: the role of new approach methodologies. [PDF]
Front ToxicolDeepika D +8 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source
Ecological and Human Health Risk Assessment of Metals in Peruvian Avocados Using a Probabilistic Approach. [PDF]
FoodsYoplac-Navarro M +7 more
europepmc +1 more source