Results 151 to 160 of about 6,269,925 (357)

Body mass index and healthy lifestyle practices among Peruvian university students: a comparative study among academic discipline

open access: yesFrontiers in Nutrition
BackgroundExcess body weight and an unhealthy lifestyle are a risk factor for noncommunicable diseases. University students are susceptible to unhealthy habits and obesity.
Jacksaint Saintila   +5 more
doaj   +1 more source

One Health Informatics [PDF]

open access: yes, 2014
Zoonoses are a class of infectious diseases causing growing concern of health authorities worldwide. Human and economic costs of zoonoses are substantial, especially in low-resource countries.
Ossebaard, Hans C.
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

The indirect approach [PDF]

open access: yes
Aid and conditionalities are the"carrots and sticks"of the conventional, direct approach to fostering economic development. The economic theory of agency is the most sophisticated treatment of the direct carrots-and-sticks approach to influencing human ...
Ellerman, David
core  

One Health Information and Communication Technology. How digital humanities contribute to public health. [PDF]

open access: yes, 2013
Zoonoses are infectious diseases that are transmitted either directly or indirectly from animals to human beings. The human and economic costs of zoonoses and antimicrobial resistance can hardly be overestimated.
Ossebaard, Hans
core   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Celebrating the work of PGRs in Human and Health Sciences [PDF]

open access: yes, 2017
The School of Human and Health Sciences is justifiably proud of its research. World renowned staff examine issues as diverse as criminal profiling, wound care and child protection.
Gavin, Helen, Hanson, Sue, Ward, Sarah
core  

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