Results 131 to 140 of about 30,135,302 (286)
Urban First Nations grandmothers : health promotion roles in family and community [PDF]
ix, 146 leaves ; 29 cmThe purpose of this participatory action research study was to gain an awareness of the meanings of health for urban First Nations grandmothers, and how they promote it in their families and communities.
Ginn, Carla S. +1 more
core
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
The problem with which human ecology confronts medical librarians is that of inherent complexity combined with vagueness of definition and thought, associated with the risk of dispersing effort and funds ineffectually and too widely. Much of this paper is concerned with explaining why ecology must primarily be concerned with the "physiology of ...
openaire +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Artificial molecular machines and motors—Design and control of nanoscale motion
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Human-centered design approaches in health sciences research [PDF]
Introduction In the rapidly evolving field of health sciences, traditional paradigms of research and innovation are being challenged by a growing recognition of the need for more inclusive, empathetic, and context-sensitive approaches.
Subedi, Madhusudan
core
Calling for a GeoHealth Decadal Survey: Accelerating Solution-Oriented Research and Applications to Address Environmental and Health Problems. [PDF]
Tong DQ +18 more
europepmc +1 more source
Science and Health in the Present Moment of Humanity
openaire +1 more source

