KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
HEALTH AND HUMAN RIGHTS: BASIC INTERNATIONAL DOCUMENTS
, 2004 Introduction -- I. Health and medical professions -- A. Professional ethics -- Declaration of Geneva (1948, 1968, 1983, 1994) -- World Medical Association International Code of Medical Ethics (1949, 1968, 1983) -- Nurses and human rights (1988 ...
Marks, Stephen P., ed.
core
Correction: Editorial: Neuromodulation techniques, mechanisms, and potential benefits for physical activity participation and human performance. [PDF]
Front PhysiolThakkar B +3 more
europepmc +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular epidemiology of pathogenic Leptospira spp. in Thailand during 2024-2025, with detection of Leptospira weilii in human clinical specimens. [PDF]
PLoS Negl Trop DisNukhonthod N +3 more
europepmc +1 more source
Celebrating the work of PGRs in Human and Health Sciences
, 2017 The School of Human and Health Sciences is justifiably proud of its research. World renowned staff examine issues as diverse as criminal profiling, wound care and child protection. Emerging themes for research in the school range from examining mental health and well-being to innovative approaches to understanding crime, from the study of national ...
Gavin, Helen, Ward, Sarah, Hanson, Sue
openaire
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Health Care Choices of Ghanaian adult Immigrants in Calgary, Alberta, Canada
, 2018 Many African immigrants moving to Canada tend to experience deterioration of health with time in their host country due to the influence of multiple factors on their health care decisions.
University of Lethbridge. Faculty of Health Sciences +1 more
core
Generative AI as a cognitive co-learner: a developmental framework for AI literacy in health sciences education. [PDF]
Front Artif IntellOo MZ +7 more
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source