Results 221 to 230 of about 30,135,302 (286)

Correction: "There's no representation": a qualitative study of attitudes and motivations towards genomic research participation among Australian South Asians. [PDF]

Eur J Hum Genet
Nathan V, Akbar H, McInerney-Leo A, Gilroy D, Henders A, Naresh R, Choudhury N, Waqar M, Shah S, Yanes T, South Asian Genes and Health in Australia (SAGHA) research team.   +10 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Climate Change Impacts on One Health Systems: A Narrative Review of Empirical Evidence and Policy Responses. [PDF]

Public Health Chall
Adamopoulos I, Eslahi AV, Syrou N, Frantzana A, Tsirkas P, Mpourazanis G, Kayusi F, Diamanti K, Mishra H, Mijwil MM, Ali G, Hrustemović E, Argüello-García R, Lamnisos D.   +13 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Exploratory study of protective factors against belief in neuromyths in in-service teachers at Brazilian vocational-technical high school. [PDF]

BMC Med Educ
Teixeira DD, Oliveira MA, Sabino-Carvalho JL, de Almeida AA.   +3 more
europepmc   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

The shadow of mercury behind gold extraction in the Amazon: hidden threats to human health and the environment. [PDF]

Lancet Reg Health Am
Valbuena Ruiz FJ, Jimenez A, Ippolito S, Miani A, Vasiliou V, Piscitelli P.   +5 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Environmentally responsible human genomic data governance: points for consideration. [PDF]

NPJ Genom Med
Ghinea N, Samuel G, Xin W, Bonser E, Cook-Deegan R, Ferrie M, Gyngell C, Otlowski M, Petersen A, Pratt B, Roczo-Farkas S, Newson AJ.   +11 more
europepmc   +1 more source