Results 231 to 240 of about 30,135,302 (286)

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

open access: yesMolecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler   +3 more
wiley   +1 more source

The future of global health partnerships: Co-investment, reciprocal learning and mutual benefit. [PDF]

open access: yesPLOS Glob Public Health
Simms B   +5 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Comparison of viral respiratory pathogens circulation among Iranian pilgrims during two large religious mass gatherings: the Hajj and Arbaeen walk 2025. [PDF]

open access: yesTrop Dis Travel Med Vaccines
Ahmadi AS   +7 more
europepmc   +1 more source

Integrating research and surveillance to mitigate zoonotic disease risk in indigenous communities: Insights from an expert group meeting in Amazonas, Peru. [PDF]

open access: yesPLoS Negl Trop Dis
Pérez JG   +19 more
europepmc   +1 more source

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